The drug is a combination drug recommended for use when symptoms of headache, joint pain, or toothache appear. The drug can be used for migraine attacks. When combined with caffeine, aspirin, and paracetamol, the medication enhances and improves the spectrum of action of the pain-relieving components.
Compound
The composition of Citramon tablets traditionally included: 240 mg of acetylsalicylic acid (ASA), 180 mg of phenacetin , 30 mg of caffeine , 15 mg of cocoa, 20 mg of citric acid.
However, at present, the classic recipe for making the drug is not used due to the withdrawal of one of its active components, phenacetin, (this is due to the high nephrotoxicity of the substance).
Numerous manufacturers produce medicines whose names contain the word “Citramon”, but they all have a slightly modified composition, in which paracetamol is used phenacetin .
Tablets from different manufacturers maintain the same uniformity of active ingredients, but the concentration of each of them may differ.
Citramon P, Citramon U and Citramon M contain active components (ASA, paracetamol and caffeine) in the same concentration as in the original drug. But in Citramon-Forte their concentration is different: each tablet contains 320 mg of ASA, 240 mg of paracetamol and 40 mg of caffeine.
Citramon Borimed tablets contain 220 mg of ASA, 200 mg of paracetamol and 27 mg of caffeine. The concentration of these substances in Citramon-LekT tablets is, respectively, 240 mg, 180 mg and 27.5 mg.
But the main difference between Citramon Ultra and Citramon is the presence of a film shell, which makes the tablet easier to swallow, acts as a reliable barrier between the mucous membrane of the digestive canal and the active substances contained in the tablets (in particular, the shell protects the stomach from the aggressive effects of ASA) and accelerates the absorption of the drug.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Citramon is a combined drug, the effect of which is determined by the properties of the components it contains (non-narcotic analgesic, psychostimulant and NSAID).
ASA relieves fever and inflammation, relieves pain (especially if the pain is caused by an inflammatory process), has a moderate antiplatelet effect, prevents the formation of blood clots, and helps improve microcirculation in the area of inflammation.
Paracetamol reduces the intensity of pain, reduces fever, and has a weak anti-inflammatory effect. The properties of this substance are associated with its influence on the thermoregulation center located in the hypothalamic region and a weakly expressed ability to inhibit the formation of Pg in peripheral tissues.
Caffeine has a direct stimulating effect on the central nervous system, which manifests itself in the form of increased excitation processes in the cerebral cortex, vasomotor and respiratory centers, increased motor activity and strengthened positive conditioned reflexes.
Stimulates mental activity, temporarily reducing or eliminating drowsiness and fatigue, and shortens reaction time. Reduces platelet aggregation.
Citramon tablets contain caffeine in low concentrations. Because of this, the substance has virtually no stimulating effect on the central nervous system, but improves cerebral vascular tone and helps accelerate blood flow.
The combination of ASA and paracetamol potentiates the analgesic effect of the drug. Both the analgesic and antipyretic effects of ASA and paracetamol are enhanced when these substances are used simultaneously with caffeine.
Pharmacokinetics
After oral administration, the components contained in the tablets are absorbed quickly and almost completely. At the same time, caffeine helps to increase F (bioavailability) of ASA and paracetamol.
During absorption, it and ASA are intensively biotransformed with the formation of pharmacologically active metabolites. Salicylic acid is formed from ASA through the process of deacetylation in the liver and intestinal wall .
Under the influence of the hepatic isoenzyme CYP1A2, caffeine forms dimethylxanthines ( paraxanthine and theophylline ).
The maximum duration of all active components of Citramon is from 0.3 to 1 hour. In blood plasma, from 10 to 15% of paracetamol and approximately 80% of the taken dose of ASA are in an albumin state.
All components of the tablets easily penetrate into any fluids and tissues of the body (including easily crossing the placental barrier and entering breast milk). Minor concentrations of salicylates are found in brain tissue, while levels of caffeine and paracetamol are comparable to plasma levels.
With the development of acidosis, ASA turns into a non-ionized form, due to which its penetration into the tissues of the NS increases.
Metabolism of active substances occurs in the liver. ASA has 4 metabolites (gentisuronic and gentisic acids, salicylophenolic glucuronide, salicylurate). Paracetamol forms sulfate (80% of the total amount) and paracetamol glucuronide (both are pharmacologically inactive), as well as a potentially toxic substance - N-acetyl-benziminoquinone (about 17% of the total amount).
Caffeine metabolites are uridine , mono- and dimethylxanthines, mono- and dimethyluric acid, di- and trimethylallantoin.
Caffeine affects the pharmacokinetics of paracetamol, slightly increasing (up to 20-25%) the formation of N-acetyl-benziminoquinone.
Metabolites are excreted by the kidneys. About 5% of paracetamol, about 10% of caffeine and about 60% of salicylates are excreted unchanged.
The half-life of elimination is from 2 to 4.5 hours (all components of the drug are excreted at approximately the same rate). Increasing the dose of Citramon leads to a slower elimination of ASA compared to other substances by up to 15 hours.
In smokers, on the contrary, there is an accelerated elimination of caffeine in comparison with other components of the drug.
Use for high blood pressure
In Citramon, the instructions for increasing or lowering blood pressure detail all available contraindications for taking Citramon. The guidelines note that treatment is prohibited in the presence of persistently elevated intracranial pressure. Taking it aggravates the condition; before starting therapy, it is necessary to conduct a laboratory diagnostic study and find out why the headache hurts.
Medical signs of high blood pressure include:
- cephalalgia - pressing, dull,
- impaired visual acuity with a feeling of blurriness,
- nosebleeds,
- dizziness.
The following symptoms appear with low blood pressure:
- dizziness,
- short-term fainting,
- decreased vision,
- weakness,
- vomit,
- nausea.
Certain medical manifestations are observed with both high and low blood pressure. To correctly assess the condition, you should take into account the following data:
- The use of the product is permitted in case of pale skin, thirst and hunger, chills (only with low intracranial pressure).
- The product should not be taken if you have symptoms of a hypertensive crisis, headaches, or throbbing in the temples.
Therapy with Citramon in the latter situation will cause aggravation of cephalalgia. Treatment is necessary only for low blood pressure, otherwise the body's reaction to the drug will be unpredictable. Doctors recommend not to take any medications uncontrollably, especially if you feel pain. Without diagnosis and proper identification of the causes of poor health, you can make things worse and provoke an exacerbation of hidden pathological processes. Headaches of the pathological type require complex therapy, and not temporary relief of symptoms with analgesics. People are interested in whether Citramon is for high or low blood pressure ? If you experience low blood pressure, this drug increases it.
Indications for use of Citramon
What is Citramon P for?
When asked what Citramon P helps with, the manufacturer answers in the annotation for the drug that the use of tablets is advisable for relieving mild and moderate pain, as well as for alleviating the patient’s condition during febrile syndrome , which is accompanied by ARVI and influenza .
Citramon is effective for the head (including during migraine attacks), for joint and muscle pain, and algodismenorrhea .
What are Citramon-LekT tablets for?
Indications for the use of Citramon-LekT are the same as for other drugs based on ASA, paracetamol and caffeine, namely: pain syndrome due to algodismenorrhea , neuralgia , myalgia , arthralgia , headache, toothache, migraine.
The drug can also be used as a remedy for fever during acute respiratory viral and influenza .
Does Citramon help with toothache?
Toothache is one of the indications for using the drug. The effectiveness of Citramon is due to the properties of its constituent NSAIDs, non-narcotic analgesic and psychostimulant.
Strengthening each other's action, these components have a complex effect on the body, relieving any pain (including toothache), especially if it is associated with inflammation. During exacerbation of chronic pulpitis , against which the temperature often rises, Citramon not only helps relieve pain and reduce the severity of inflammation, but also has an antipyretic effect.
Characteristics of the drug
The main component in the composition is caffeine. It activates the central nervous system, increases the degree of arousal, and is used for:
- activation of respiratory, brain, vasomotor centers,
- reducing the lumens of blood vessels,
- increased breathing,
- muscle relaxation,
- stabilization of the heart, diuresis.
Citramon is approved to block several types of headaches. It is used to increase blood pressure levels in a single dose if there are no signs of hypertension. Caffeine allows you to gently gain weight and normalize sleep. Allowed for complex therapy in combination with ergot alkaloids and analgesics.
The second substance is acetylsalicylic acid. Aspirin relieves mild to moderate pain and is used to block the inflammatory process and reduce fever. Can be used as a medicine to prevent arterial or venous thrombosis. The substance helps to temporarily relieve discomfort associated with chronic lupus, rheumatoid arthritis, and osteoarthritis. Included in a complex to reduce the risk of death, the formation of unstable angina or myocardial infarction.
The third substance is paracetamol. The substance is used to eliminate pain and reduce fever. It does not have anti-inflammatory or antiplatelet effects. The substance is added to many medications and eliminates acute respiratory infections in the early stages of their occurrence.
We studied the composition of Citramon. It is aimed at influencing intracranial pressure in the direction of growth. The product does not cause dilation of blood vessels. Citramon increases low blood pressure .
Citramon increases or decreases blood pressure
Contraindications
The instructions list the following contraindications for Citramon:
- complete or partial combination of recurrent polyposis /paranasal sinuses, bronchial asthma and intolerance to NSAIDs or ASA (including a history);
- hypersensitivity to the components of the tablets;
- erosive and ulcerative lesions of the gastrointestinal tract in the acute phase;
- gastrointestinal bleeding ;
- portal hypertension;
- hemophilia;
- hypoprothrombinemia;
- hemorrhagic diathesis;
- vitamin deficiency K;
- Severe ischemic heart disease;
- severe arterial hypertension ;
- renal failure;
- deficiency of the cytosolic enzyme G6PD;
- pregnancy (especially its first and last trimesters);
- lactation;
- increased excitability;
- glaucoma;
- dissecting aortic aneurysm;
- sleep disorders;
- surgical interventions accompanied by bleeding;
- childhood (in children under fifteen years of age with hyperthermia against the background of a viral infection, there is a high probability of developing Reye's syndrome );
- concomitant use of anticoagulants .
Relative contraindications are gout and existing liver pathologies.
Side effects
Side effects of Citramon:
- gastralgia , anorexia , nausea, formation of erosions and ulcerative elements on the mucous membrane of the digestive canal, gastric and intestinal bleeding;
- liver failure;
- hypersensitivity reactions (including the development of symptoms of the Fernand-Vidal triad );
- interstitial nephritis , nephrotic syndrome , necrotizing papillitis , with long-term use - renal failure ;
- anemia , thrombocytopenia , leukopenia ;
- acute fatty hepatosis , toxic hepatitis , acute hepatic encephalopathy ( Reye's syndrome );
- worsening heart failure , manifestation of its latent forms (with long-term use);
- dizziness, insomnia, agitation, anxiety, headache, tinnitus, hearing and vision impairment, aseptic meningitis ;
- increased blood pressure, arrhythmia , tachycardia ;
- development of tolerance and weak psychological dependence (with long-term use of high doses of the drug);
- drug-induced headache after discontinuation of Citramon (if the drug was used for a long time).
Experiments on animals also demonstrated the teratogenic effect of the drug on the fetus.
Citramon tablets, instructions for use
Preparations from different manufacturers have different compositions, and since they often contain active substances in different concentrations, you should read the instructions very carefully so as not to mistakenly exceed the permissible daily dose.
What all drugs have in common is that they can be used as an analgesic for a maximum of five days, and as an antipyretic for three days.
Instructions for use Citramon P and Citramon-LekT
Citramon P and Citramon-LekT can be taken from the age of fifteen. Take one tablet 2-4 times a day (during or after meals). The break between doses should be at least four hours. The average dose is 3-4 tablets per day.
Citramon for headaches (as well as in other cases when it is necessary to relieve severe pain) can be taken 2 pieces at once. The permissible upper limit of the daily dose is 8 tablets.
Treatment lasts from one week to ten days.
If necessary, the doctor may prescribe a different dose of the drug or select a different treatment regimen.
Instructions for use Citramon Forte
Citramon-Forte is used in patients over sixteen years of age. The daily dose is 2-3 tablets. You need to take them one at a time, 2 or 3 times a day. To relieve an attack of acute pain, you should immediately take two tablets.
The permissible upper limit of the daily dose is 6 tablets.
Citramon-Darnitsa is taken according to a similar regimen (the only difference between the drug is the age limit - these tablets are prescribed from 15 years of age).
Instructions for use Citramon-Borimed
It is preferable to take Citramon-Borimed immediately after meals or between meals. The drug can be used in adults and adolescents over fifteen years of age. Take one tablet 2-3 times a day, maintaining intervals of at least 6-8 hours between doses. The highest single dose is 2 tablets, the daily dose is 4.
It is used as an antipyretic at temperatures exceeding 38.5 °C (if there is a tendency to febrile convulsions - at temperatures above 37.5 °C). Single dose - 1-2 tablets.
Instructions for use of Citramon Ultra
Citramon Ultra is prescribed from the age of fifteen. Daily dose - 1-3 tablets. If necessary, you can take up to 6 tablets during the day.
First aid
With a high pulse and hypotension, you need to be able to provide timely assistance. The heartbeat must be slowed down and blood pressure increased.
If the attack is not stopped in time, the situation may worsen even further.
You definitely need to lie down, raise your legs just above head level, unfasten the buttons on your clothes, loosen the belt on your trousers or the belt on your dress, and unfasten your shoes. You should do everything to be able to breathe calmly and deeply. To do this, you need to open the windows and doors, ensure a flow of fresh air, and turn on the fan to heat it up.
Sweet tea helps a lot. You can even drink two cups at once. If this is not possible, you should slowly suck on a couple of pieces of refined sugar or simply put a spoonful of loose sugar (sand) in your mouth. A piece of dark chocolate will also help increase blood pressure, but this is only if there is no vomiting.
If you feel hungry during an attack, you are allowed to eat a sandwich with cheese, but without butter, so as not to provoke nausea. You need to chew your food slowly and bite a little at a time.
To slow down your pulse, you need to take deep breaths, holding your breath for a few seconds. Tension of the abdominal muscles and pressure with your thumbs on the upper eyelids directly under the eyebrows also help.
Important!
In case of a severe attack, you should not take medications. The maximum you are allowed to drink before the ambulance arrives is Citramon.
Overdose
A slight overdose manifests itself in the form of nausea, dizziness, increased pallor of the skin, gastralgia, vomiting, and ringing in the ears.
Symptoms of severe intoxication of the body: impaired circulation and breathing, anuria , anxiety, stupor, nausea, headache, hyperthermia , tremor , drowsiness, anxiety, sweating, collapse , bleeding, convulsions (with pathological increased tendon reflexes), coma .
If signs of overdose appear, taking the tablets should be stopped. To prevent the absorption of the drug in the digestive canal, the patient's stomach is washed, enterosorbents and a saline laxative are given.
If the plasma concentration of salicylates in a child exceeds 300 mg/l, and in an adult - 500 mg/l, it is advisable to carry out forced alkaline diuresis. To maintain urine pH at 7.5-8, alkalizing agents are administered.
Measures are taken to restore the bcc and acid-base balance.
In case of cerebral edema, mechanical ventilation with an oxygen-enriched mixture is prescribed in the mode of creating PEEP (positive end-expiratory pressure). Hyperventilation should be carried out in combination with the use of osmotic diuretics .
If there are signs of liver damage, N-acetylcysteine, which is a specific antidote to paracetamol, should be administered. The solution is used orally and injected into a vein. In total, the patient needs to administer seventeen doses: the first - 140 mg/kg, all subsequent doses - 70 mg/kg.
The most effective therapy is started in the first ten hours after the development of intoxication. If more than 36 hours have passed, treatment is ineffective.
When the prothrombin index (PTI) value increases to 1.5-3, the use of phytomenadione ( vitamin K ) in a dose of 1 to 10 mg is indicated. If the PTI exceeds 3.0, infusion of clotting factor concentrate or native plasma should be started.
Carrying out hemodialysis, using antihistamines , corticosteroids or acetazolamide (to alkalinize urine) during intoxication with Citramon is contraindicated.
These measures can provoke the development of acidemia and increase the toxic effect of ASA on the patient’s body.
Treatment
Tachycardia in combination with hypotension is treated both with special drugs prescribed by the doctor and with the help of folk remedies. The second option is suitable if the symptoms are not too pronounced and if the attacks are rare. Traditional medicine helps, but more for prevention. But if the situation is serious, medical treatment cannot be avoided.
Medicines
Medicines are prescribed only by a doctor and only after a complete examination. Self-medication is very dangerous because it can only worsen the situation. If you take blood pressure-raising medications at your own discretion, your pulse will increase even more, and if you take antihypertensive pills, your blood pressure will drop even more.
Most often, for hypotension with increased heart rate, the following is prescribed:
- Anapril, Concor and other beta-blockers that have a pronounced antiarrhythmic effect;
- Celanide, Digoxin and other glycosides;
- For example, Cardio-Forte and other drops to stimulate the heart;
- Asparkam, Panangin and other tablets to prevent a lack of magnesium and potassium in the body;
- Corvalol, Nottu and other sedatives;
- tranquilizers such as Relanium.
Take note!
If dehydration occurs along with illness, it is recommended to drink Regidron, which will help restore balance in the body.
Folk remedies
The use of folk recipes helps to gently and effectively relieve ailments, as well as prevent the occurrence of similar symptoms in the future.
Rose hip decoction will help normalize your pulse. 2 tbsp. Add 400 ml of water to the fruit, bring to a boil, boil for 15 minutes, cool, strain. Take 100 ml three times a day. The drink has a pronounced antimicrobial and immunity-boosting effect.
A sedative drink that helps strengthen the heart muscle is prepared from motherwort. Pour a glass of boiling water over a spoon, cover and leave until it cools completely. Take 200 ml once a day before lunch.
A decoction of valerian has a similar effect. Pour a spoonful of crushed root into a glass of water, boil for an hour, then leave until completely cool. Take a dessert spoon three times a day.
Take note!
For traditional recipes to work, you must take them for at least 3 weeks.
Interaction
It is strictly forbidden to prescribe in combination with Citramon with:
- MAO inhibitors (when used simultaneously with caffeine , these drugs can lead to a dangerous increase in blood pressure);
- Methotrexate at a dose exceeding 15 mg/week. (this combination increases the hematological toxicity of methotrexate).
Citramon also enhances the toxicity of barbiturates and valproic acid , the effects of opioid analgesics, oral hypoglycemic and sulfonamide agents, Digoxin and triiodothyronine .
Phenytoin , ethanol , COCs, Rifampicin , tricyclic antidepressants, barbiturates, Phenylbutazone increase the toxicity of paracetamol to the liver.
Macrolides ( Erythromycin , Clarithromycin ), interferon preparations, antimycotic agents ( Fluconazole , Ketoconazole ) slow down the metabolism of the active substances of Citramon tablets and lead to an increase in their concentration in plasma.
The use of the drug in combination with platelet , indirect anticoagulants and thrombolytic agents increases the risk of bleeding.
By inhibiting the synthesis of Pg in the kidneys, it weakens the effect of potassium-sparing and loop diuretics, as well as antihypertensive drugs from the group of ACE inhibitors.
GCS increase the toxicity of the components of the tablets on the gastric mucosa, increase the clearance of ASA and reduce its plasma concentration.
In combination with beta-adrenergic agonists ( Fenoterol , Salbutamol , salmeterol ) in high doses, the risk of developing hypokalemia ; with methylxanthines , the level of theophylline in plasma increases and the risk of its toxic effect increases; with Li salts, the plasma concentration of Li+ ions increases.
Due to the competitive excretion of uric acid in the nephron tubules, it weakens the effect of uricosuric drugs.
Side effects
Citramon for high or low blood pressure is prescribed without a prescription; it can be bought at any pharmacy. Despite its harmless composition, it has side effects.
Citramon side effects
A person may notice the following conditions:
- If there is an overdose, then dyspeptic disorders appear: vomiting, diarrhea, nausea.
- The composition contains acetylsalicylic acid, which has an irritating effect on the mucous membrane of the stomach and intestines. Therefore, when using Citramon, pain, abdominal discomfort, and ulcers in the gastrointestinal tract may appear.
- The appearance of nosebleeds or stomach bleeding. If bleeding is minimal, you should stop taking the drug and use a hemostatic agent. If there is massive blood loss and the condition worsens, you should urgently call an ambulance.
- Large dosages of Citramon with long-term use have a negative effect on the liver. One of the substances of this drug (paracetamol) has a hepatotoxic effect. At a moderate dosage, the drug does not have a negative effect on the body.
special instructions
Abuse of caffeine-containing products during treatment with Citramon can provoke overdose symptoms.
Elderly people, people suffering from gout , impaired renal and/or liver function with benign hyperbilirubinemia should be careful when taking tablets.
In patients with allergic complications (allergic rhinitis, asthma, urticaria ), when they are combined with respiratory tract infections, as well as with increased sensitivity to NSAIDs during treatment, bronchospasm or asthma attacks are possible.
With long-term (more than five days in a row) use of Citramon, monitoring of the functional state of the liver and peripheral blood patterns is necessary.
Long-term use of tablets containing paracetamol in high cumulative doses in some cases can cause drug-induced nephropathy or irreversible renal failure .
Long-term use of painkillers to treat headaches often leads to chronic headaches.
Taking Citramon can distort laboratory test indicators such as: plasma concentration of uric acid, plasma concentration of Heparin , plasma concentration of theophylline, blood sugar level, concentration of amino acids in the urine.
The drug may alter doping control tests in athletes. It complicates the diagnosis of “acute abdomen”.
In case of long-term treatment with Citramon, you should consult a doctor before taking Ibuprofen .
The use of drugs containing ASA during surgical interventions (including dental operations) increases the likelihood of the occurrence/intensification of bleeding.
The drug may affect the rate of neuromuscular transmission, and therefore during the period of treatment they should refrain from driving a vehicle or operating dangerous machinery.
The effect of the drug on blood pressure. Do Citramon tablets increase or decrease blood pressure?
Headaches are a fairly common occurrence in people prone to changes in blood pressure. Therefore, questions naturally arise here: is it possible to take the medicine with high blood pressure, is the drug harmful for hypotensive patients, how are Citramon and blood pressure related?
The analgesic effect for headaches is provided primarily due to the presence of ASA and paracetamol in the tablets.
The third component of the drug - caffeine - increases the flow of oxygen to tissues, stimulates blood circulation in the brain and increases blood pressure, thus helping to reduce the intensity of headaches and enhancing the effects of other components of Citramon.
High doses of caffeine provoke depression of the central nervous system. When taking small doses (as, for example, in Citramon), the stimulating effect predominates.
It should be noted that while caffeine increases blood pressure, which is reduced during hypotension, it does not change normal blood pressure.
Effect on low blood pressure
The list of clinical manifestations of low blood pressure includes attacks of dizziness, problems with visual acuity - especially when driving vehicles. These symptoms are caused by low blood pressure and can contribute to loss of concentration and reaction speed. Unpleasant symptoms are suppressed by Citramon.
A low blood pressure level may signal other pathologies. A list of common diseases and conditions is presented:
- massive bleeding;
- complex infectious process;
- dehydration;
- heart attack or failure;
- severe allergic reactions;
- diseases of the endocrine department with damage to the thyroid gland, a drop in blood glucose, and the development of diabetes mellitus.
Doctors do not recommend constantly using the medicine to regulate blood pressure. The drug has a short-term type of action and is not suitable for this therapy.
Thanks to the caffeine included in the composition, the medication increases blood pressure levels rather than lowering them. It is included in many common foods that the patient consumes daily. Coffee lovers are addicted to it. A similar condition is observed with regular use:
- strong black tea;
- Coca-Cola, Pepsi-Cola or competitive drinks;
- energy workers.
In people who prefer this type of drink, the body is accustomed to a regular supply of caffeine. Taking tablets containing it will not affect the level of intracranial pressure and will not be able to increase the indicators.
Analogs
Level 4 ATC code matches:
Acetylsalicylic acid
Aspirin-S
Citropak
Aspirin
Coficil-Plus
Farmadol
Askofen-P
Cefekon N
Aquacitramon
Upsarin UPSA
Citrapack
Alca Prim
Thrombopol
Citrapar
Analogs with the same composition of active ingredients:
- Citramon-Darnitsa
- Citramon-Borimed
- Citramon-Ultra
- Citramon-LekT
- Aquacitramon
- Atsepar
- Askofen-P
- Cofficil-plus
- Citrapar
- Excedrin
- Migrenol Extra
Can children take Citramon?
The use of ASA-containing drugs for the treatment of ARVI in children (with or without hyperthermia
With some viral infections (particularly those caused by varicella zoster or influenza A or B ), there is a risk of developing acute hepatic encephalopathy ( Reye's syndrome ), which requires immediate medical attention. One of the signs of Reye's syndrome is prolonged vomiting.
Taking into account the above reasons, the use of tablets in patients under sixteen years of age is contraindicated.
Since the drug has a large number of side effects, it is better for children with a headache or toothache to choose safer remedies.
Alcohol compatibility
During treatment with Citramon, you should avoid drinking alcohol, since alcohol increases the likelihood of a toxic effect of paracetamol on the liver and ASA on the gastrointestinal tract.
The use of ethyl alcohol with ASA contributes to damage to the mucous membrane of the digestive canal. The synergism of alcohol and ASA also results in prolongation of bleeding time.
Citramon for hangover
Citramon for a hangover is not the most advantageous option, since the use of this drug allows you to relieve headaches only temporarily, but does not eliminate the main causes of poor health - imbalance of water and electrolytes, as well as intoxication.
The headache that accompanies hangover syndrome is associated with impaired venous outflow from the head, tissue swelling (in particular, swelling of the meninges ) and inhibition of the analgesic (antinociceptive) system, part of which is the action of serotonin and dopamine.
ASA partially unloads the membranes of the brain, caffeine stimulates metabolism in neurons and has an invigorating effect, cocoa reduces the relative deficiency of intracerebral serotonin and dopamine, citric acid reduces the severity of symptoms of alcohol intoxication.
However, the paracetamol contained in the tablets puts a lot of strain on the liver, which, in combination with alcohol breakdown products, can aggravate hangover symptoms and damage the body.
Diagnostics
With regular attacks of tachycardia in combination with hypotension, you should seek help from a doctor. First, you should visit your family doctor or therapist, who will issue directions for tests and, based on them, determine which specialist to go to next. Most likely, this will be a cardiologist or endocrinologist, pulmonologist, or less often an oncologist. Don't be surprised at the many checks that will be carried out during the inspection. To determine the cause of the malaise, measurements of pulse and pressure must be carried out under different physical activity, at different breathing rates, under different weather conditions.
Tests may also need to be taken several times.
Citramon during pregnancy and lactation
Can pregnant women drink Citramon?
During pregnancy, you should avoid taking Citramon tablets, since the ASA they contain has a teratogenic effect.
The use of Citramon during pregnancy in the 1st trimester can cause cleft palate ; the use of the drug in the 3rd trimester leads to a deterioration in labor (suppression of Pg synthesis) and closure of the ductus arteriosus in the fetus. This in turn provokes hyperplasia of the pulmonary vessels and increased pressure in the vessels of the pulmonary (pulmonary) circulation.
Thus, the answer to questions like “Can I drink Citramon during pregnancy?” and “Can pregnant women take Citramon?” unambiguous - impossible.
Can a nursing mother take Citramon while breastfeeding?
The use of the drug during hepatitis B is contraindicated. The active components of the tablets and their metabolites are excreted into breast milk, which increases the likelihood of platelet dysfunction and bleeding in the baby.
The dangers of low blood pressure and high pulse
Hypotension in combination with tachycardia is very dangerous. This symptom not only causes weakness of the heart muscle, but also leads to constant shortness of breath, weakness, and decreased performance.
A malaise that many do not take seriously leads to:
- heart attacks and strokes;
- Alzheimer's disease;
- ischemia;
- dementia.
Often such health problems end in death.
The best prevention of high heart rate with low blood pressure is a healthy lifestyle, sufficient physical activity, regular contrast showers, and the presence of foods high in potassium and magnesium in the diet.
If problems cannot be avoided, do not postpone your visit to the doctor. A timely and correctly drawn up treatment regimen will help avoid disastrous consequences and restore health.
Reviews
Most people, despite the fact that the drug is considered potentially unsafe, leave good reviews about Citramon, calling it their savior from headaches (including migraine attacks).
Although there are also those that mention the dangers of tablets for the liver and gastrointestinal tract, and also that with long-term use they cause a kind of addiction (patients can no longer do without Citramon for a long time and experience a constant need for it).
Based on all available reviews, the following conclusion can be drawn: the pills should be taken taking into account existing contraindications, as well as having previously compared the expected benefits from them and potential risks.
One or two tablets taken to relieve an attack of pain are not capable of harming the body; systematic, uncontrolled use, of course, threatens with very serious consequences.
Citramon price
The price of Citramon depends on which company produced the drug. So, for example, the price of Citramon P is from 15 rubles, and the price of Citramon Ultra is from 50 rubles.
In Ukraine, a package of tablets can be purchased from 5 to 20 UAH.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Citramon P tablets 20 pcs. Anzhero-Sudzhensky plant LLC Avexima Siberia
59 rub. order - Citramon-ExtraCap capsules 240 mg + 27.45 mg + 180 mg 10 pcs. Pharmstandard-Leksredstva OJSC
73 rub. order
- Citramon P tablets 20 pcs. Pharmstandard-Leksredstva OJSC
62 RUR order
- Citramon P Medisorb tab. 20 pcs. JSC Medisorb
35 rub. order
- Citramon P tablets 20 pcs. AO Update PFK
81 RUR order
Pharmacy Dialogue
- Citramon-P tablets No. 20Update PFK CJSC
88 rub. order
- Citramon-P Update tablet No. 10Update PFK CJSC
58 RUR order
- Citramon-ultra tablets No. 20PharmVilar
71 RUR order
- Citramon-ultra tablets No. 20 PharmVilar NPO LLC/Obolenskoye FP JSC
77 RUR order
- Citramon-ultra tablets No. 10 Obolenskoe pharmaceutical company.
54 RUR order
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Pharmacy24
- Citramon-M No. 6 tablets PAT "Khimpharmzavod" Chervona Zirka", Kharkov, Ukraine
4 UAH. order - Citramon Fitofarm forte N12 capsules PRAT "Fitofarm", Ukraine
20 UAH order
- Citramon-M No. 10 tablets PAT "Khimpharmzavod" Chervona Zirka", Kharkov, Ukraine
5 UAH order
- Citramon Euro N10 tablets Mibe GmbH Arznam., Germany
32 UAH order
- Citramon-forte No. 100 tablets PAT "Lubnipharm", Ukraine
85 UAH order
PaniPharmacy
- Citramon In tablet Citramon In tablet. No. 6 Ukraine, Lubnyfarm PJSC
3 UAH order
- Citramon F tablets Citramon tablets. No. 6 Ukraine, Fitofarm ChAO
4 UAH order
- Citramon M tablets Citramon-M tablets. No. 10 Ukraine, Red Star JSC
6 UAH order
- Citramon tablets Citramon-Darnitsa tablets No. 6 Ukraine, Darnitsa ChAO
7 UAH order
- Citramon tablets Citramon-Darnitsa tablets No. 10 Ukraine, Darnitsa ChAO
13 UAH order
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