Spinal hemangioma is a benign tumor that develops in the vertebral body, while excessive proliferation of blood vessels occurs in the medulla. This tumor usually develops in the lower thoracic or upper lumbar spine. As a rule, hemangioma occurs in one vertebra. Vertebral hemangioma is quite common and is observed in almost 10% of the population. Most often, hemangioma is discovered accidentally and is asymptomatic. Hemangioma is more common in adults and rare in children. These formations are generally considered to be venous malformations of the vertebral bodies.
Definition
Any hemangioma, including a vertebral one, is a vascular tumor. The name of this tumor can be deciphered as heme (blood) + angio (vessel) + “-oma”, that is, a tumor originating from blood vessels. The only place where hemangioma cannot occur is a place where there are no vessels: the optically transparent media of the eye and articular surfaces, where there is cartilage tissue. What cells are the source of the tumor? This is the endothelium, the inner lining of blood vessels.
Patients with a hemangioma should not worry that the tumor will become cancerous. Hemangioma is one of the few neoplasms that never malignize, that is, do not turn into malignant ones.
Hemangioma of this localization is always located deep in the spongy bone substance of the vertebral body, saturated with blood vessels. This is an advantageous localization, since the vascular tangle is protected on all sides by bone. Hemangiomas, which are located in the parenchyma of internal organs, for example, inside the liver, are not protected from external influences, and in case of injury they can be a source of massive bleeding.
From the late eighties of the 20th century to the present day, the number of detected hemangiomas of internal organs, including vertebrae, has increased significantly due to the massive introduction of new imaging diagnostics - computed tomography and magnetic resonance imaging. Almost always it is an accidental finding when research is carried out for a completely different reason.
CT diagnosis of vertebral hemangiomas and their differences from metastases
Hemangioma is a benign tumor consisting of dilated vascular lacunae and perivascular fat. According to Tager I.L., hemangiomas can be considered not tumors, but a variant of the development of blood vessels in the vertebra, or a manifestation of involutive changes in the vessels and cancellous bone.
Get a CT or MRI of the spine in St. Petersburg
Hemangioma can be found in almost any organ, including spongy bones. It does not become malignant, does not metastasize, and is detected in approximately every 8-10 patients as an incidental finding on CT, MRI or radiography of the spine. Most often, hemangiomas are detected in the vertebral bodies of the thoracic spine, then in the lumbar spine, and most rarely in the cervical spine. The frequency of hemangiomas depends on age: according to I. L. Tager, vascular tumors are detected approximately 4 times less often in young patients than in older patients.
HISTOLOGICAL STRUCTURE AND CLASSIFICATION OF SPINAL HEMANGIOMA
According to the classification of A. I. Abrikosov, hemangiomas are usually divided into: cavernous - the most benign, not prone to destructive growth, consisting of many pathologically altered, dilated vessels and perivascular fat; capillary , consisting of small, practically undilated vessels; and also - the rarest - hemangioendotheliomas - the most unfavorable prognostically, capable of leading to destruction of the vertebra as in malignant tumors.
According to T.P. Vinogradov’s classification, the following vascular tumors are classified as benign: hemangioma, hemangiopericytoma, glomangioma ; and malignant: angiosarcoma, hemangioendothelioma, malignant hemangiopericytoma.
According to the classification of Slynko E.I. and Zozulya Yu.A. - the most modern (2000), the following benign varieties of angiomas are distinguished: angiolipoma, angiofibroma, aneurysmal bone cyst , and malignant: hemangiosarcoma, hemangioendothelioma, hemangiopericytoma, neoplastic angioendotheliomatosis.
CLINICAL MANIFESTATIONS OF SPINAL HEMANGIOMA
Most often, cavernous hemangiomas of the spine do not produce symptoms. Capillary hemangiomas and hemangioendotheliomas can provoke pain, impaired sensitivity and movement in the lower extremities such as unilateral or bilateral plegia, paresis, but only in the following cases:
1) When a tumor grows into the radicular canal or when it compresses the root, monoplegia or monoparesis occurs - a complete absence or decrease in the possibility of independent movements in the limb on one side, pain of a certain localization. For example, when a tumor grows into the root canal in the lumbosacral segment of the spine on the left, the pain will radiate to the left buttock and spread along the back of the thigh and lower leg.
2) When it grows into the spinal canal, with hemorrhages in the extradural space and compression of the dural sac by a hematoma, lower paraparesis or paraplegia may occur - the inability to move independently in both lower extremities, decreased sensitivity below the site of the lesion, as well as severe pain in the lower back.
3) With a pathological compression fracture of the vertebra against the background of hemangioma, a clinical picture of spinal cord injury, compression, damage and (or) compression of the roots, pain syndrome may occur - depending on the degree of compression of the spinal cord, the severity and direction of displacement of fragments.
WHAT DOES A SPINAL HEMANGIOMA LOOK LIKE ON RADIOGRAPHY, CT, MRI
CT scan identifies an area in the vertebral body, in its arch, pedicles or articular processes, most often spherical or ellipsoidal, or irregular in shape. The sizes of hemangioma are different - on tomograms you can see a tumor starting from 0.5 cm. Rarely there are giant vascular formations that occupy almost the entire volume of the vertebra. The X-ray density of this area is reduced compared to the density of the spongy substance and, especially, the endplates.
The image shows a cross section through a vertebra. In the vertebral body there is a typical hemangioma (H). Number 1 indicates thickened and sparse trabeculae of the spongy substance, number 2 indicates perivascular spaces and vascular lacunae. On computed tomography, they have a low density approaching that of fat (hemangiolipoma).
Typical hemangioma in the thoracic vertebra. On the axial section - on the right - a characteristic “dotted” “pattern” is clearly visible, caused by thickening of the trabeculae and a large amount of perivascular fat.
A small vascular tumor in the lateral parts of the body of the first lumbar vertebra. Computed tomography revealed a hypodense area with a density of -25...-30 Hounsfield units, with typical thickened and “sparse” trabeculae of the spongy substance.
Depending on the amount of perivascular fat, the density of hemangioma can range from +200 Hounsfield units to -40 or less, but almost never reaches the density of adipose tissue (-100 Hounsfield units). In the structure of the tumor, multiple trabeculae, sparse and thickened to 1-3 mm, are visible, giving a characteristic “small-dot” pattern on axial sections and a “striped” pattern on axial and coronal images. After administration of a contrast agent, the tumor stroma may be enhanced, often quite significantly. Vascular tumors are most dense during the arterial phase of contrast. The contrast from the vascular lacunae is washed out quickly, so already in the venous phase the density of the formation is significantly reduced.
Hemangiolipoma, not a very typical localization in the arch of the thoracic vertebra. The density of the area marked with an arrow approaches the density of fat (about 90 Hounsfield units).
What does a vertebral hemangioma look like on MRI? On MRI, the signal characteristics of vertebral hemangioma may vary depending on the amount of fat in the tumor structure. If there is a lot of perivascular fat, the signal from the tumor is “quenched” in the STIR mode (a special mode for suppressing the signal from adipose tissue) - the hemangioma becomes hypointense. In this case, it is customary to talk about hemangiolipoma or angiolipoma.
An X-ray description of a spinal hemangioma may be as follows: “a low-intensity area is detected in the vertebra, with smooth edges, clear contours, and a heterogeneous structure due to the presence of thickened trabeculae of spongy substance.” There is also a relationship between the amount of fat and X-ray density - the more fat, the higher the contrast with the surrounding spongy substance.
Different types of hemangiomas appear differently on x-rays. Above is a description of the most common cavernous hemangioma; with the capillary type of vascular tumor, the structure of the vertebra becomes finely cellular, the vertebra may look “swollen,” which simulates the picture of a primary malignant tumor or metastasis. Hemnagioendothelioma can destroy the vertebra, growing into the endplates, arch, spinal and root canals.
Against the background of vertebral hemangioma, especially if you play sports and apply axial load, you can provoke a pathological fracture. In this case, diagnosing the formation may become difficult, since the characteristic structure of the tumor will most likely not be traced. If a fracture is present, it is necessary to exclude a malignant tumor, including a secondary one (metastasis). In some cases, scintigraphy may also be required.
SIGNS OF HEMANGIOMA PROGRESSION
What signs may indicate the growth of hemangioma, or an atypical or malignant variant of angioma?
1) Spread of the tumor to the posterior parts of the vertebra - the arch, transverse and articular processes, spinous process.
2) Spread of the tumor to the transverse costal joint and to the proximal (initial) parts of the rib with a typical angiomatous change in its structure.
3) The appearance of local or diffuse swelling of the vertebral body, disruption of its normal shape.
4) The occurrence of Schmorl's hernias, especially large ones, with “breaking” of the endplates.
5) The occurrence of a compression fracture.
DIFFERENCES OF HEMANGIOMA FROM METASTASES
It is very important to distinguish a hemangioma from a probable malignant tumor, including a secondary one. Spinal hemangioma can be atypical, primarily multiple - in this case it can be difficult to distinguish them from secondary lesions. In such cases, a second opinion helps. There are main signs, based on which, you can distinguish metastases from hemangiomas:
1) Localization. Cavernous hemangiomas are usually located in the spongy substance of the vertebral bodies; metastases can also affect the arch, articular and transverse processes, and the spinous process.
2) Shape and dimensions. Non-specific sign, size and shape of hemangiomas can vary. However, there is a tendency for metastases to often have an irregular shape.
3) Structure and density. Cavernous hemangiomas are never hyperdense (sclerotic); the structure of the bone tissue in cavernous hemangiomas changes, but the trabeculae of the spongy substance can be traced. Sclerotic and lytic metastases cause disruption of the vertebral structure, the typical course of trabeculae is disrupted.
4) Impact on the vertebra. Intraosseous metastases cause “swelling” of the vertebra; benign hemangioma does not have a volumetric effect. Cavernous hemangioma also never causes bone lysis or destroys endplates.
5) Presence of a primary focus. If a primary tumor is identified, as well as multiple lesions of the spine, we can conclude that they are not multiple hemangiomas. Thus, cancer of the kidney, breast, and prostate often metastasizes to the bones.
WHAT TO DO WHEN A HEMANGIOMA IS DETECTED IN A VERTEBRATE?
How to treat spinal hemangioma? If the hemangioma is small and the risk of pathological fracture is low, nothing needs to be done. If there is any doubt about whether a hemangioma is typical, the doctor may recommend a follow-up study in 3-6 months.
Is it worth operating on a spinal hemangioma? The operation is indicated in the following cases:
- The tumor is large and there is a risk of vertebral fracture against this background
- The growth of hemangioma has been proven based on the results of repeated CT or MRI studies
- The formation according to the results of tomography has atypical or malignant features
Surgical treatment includes vertebroplasty or tumor sclerosis. The final decision on the need and methods of surgery is made only by a neurosurgeon or orthopedic traumatologist!
In addition, in controversial cases and doubts about the diagnosis, it makes sense to get a Second Opinion and contact an experienced radiologist who will re-analyze your CT and MRI images. As a result of such analysis, the risk of error is reduced. You can order such a consultation without leaving your home. It is enough to upload MRI images from disk into the National Teleradiological Network (NTRS) system, and doctors from leading specialized centers will carefully interpret the sent images.
Vasily Vishnyakov, radiologist
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Pavel Popov
Candidate of Medical Sciences, Member of the European Society of Radiologists
Causes of hemangiomas and statistics
Modern medicine cannot name a single exact cause of the appearance of hemangiomas, including those with vertebral localization. Most often, this is a congenital appearance of tumors associated with a genetic predisposition. In this case, the hemangioma always begins at the stage of intrauterine development, or immediately after birth.
Occasionally, in newborn children, more than three different localizations of hemangiomas on the skin can be counted. In this case, there is a high probability of tumors appearing in internal organs, including the vertebrae. This multiple condition is called hemangiomatosis.
It is assumed that acquired hemangiomas can arise, but exactly how is unclear. Possibly with prolonged exposure to ultraviolet rays from the sun, but no convincing evidence has yet been presented. Therefore, if you accidentally found a hemangioma during a CT or MRI, it is impossible to say when it formed. It could appear in the last months of intrauterine development, or a year ago.
In both men and women, these formations occur with the same frequency, in every 10th person. If we assume that each of us has 24 vertebrae, not counting the sacrum and coccyx, then the chance that any vertebra will be affected by a hemangioma during our lifetime will be 1/240. Since the causes are unknown, the methods of prevention are unknown, as well as possible, as yet unstudied and undiscovered risk factors.
Causes of hemangioma
Spinal hemangioma occurs when improper (chaotic) division of vascular tissue cells occurs. What this depends on is still a matter of debate in scientific circles. However, it has been noted that the main factor in most cases is heredity. Studies have shown that such a tumor can also occur with increased levels of estrogen, so it is most often found in women. The disease also occurs when there is heavy load on the spine, for example, during pregnancy or when lifting heavy objects.
What is the danger of hemangiomas?
Hemangioma can be growing, or it can be stable. A stable small hemangioma does not pose any danger. Before X-ray and magnetic resonance imaging were introduced into clinical practice, hemangiomas were also identified during X-ray examination as a light spot against the background of the vertebral body, as a loss of bone tissue. There were no specific signs of hemangiomas, and therefore an intravital diagnosis was rarely made, only in the case of a growing tumor leading to fractures of the vertebral bodies. The diagnosis was made during surgery, after a biopsy of intraoperative material and histological examination.
Since hemangioma is not capable of malignancy, it carries only the danger of mechanical destruction of vertebral tissue, and the occurrence of three complications:
- compression fracture of the vertebral body (most common);
- compression of the central canal with the development of compression myelopathy and the development of corresponding neurological symptoms, depending on the level (less often);
- compression of the canal with injury from bone fragments of the dura mater and (or) penetrating injury to the spinal cord (very rarely).
Fortunately, hemangioma of the vertebral body never produces profuse bleeding, since, unlike parenchymal tissue of the liver, kidneys or spleen, bone requires a small volume of blood supply. A complication such as bleeding is not recorded with vertebral hemangioma. But if a fracture has already occurred, but no operation followed, then the hemangioma can bleed in a closed volume, damaged by vertebral fragments.
FAQ
Does spinal hemangioma hurt?
Spinal hemangioma at an early stage of development rarely provokes the appearance of acute pain. Discomfort appears during physical activity and sudden movements, but quickly passes. Pain is typical for formations that reach 1 cm in diameter - they must be treated or removed promptly, otherwise the patient’s quality of life will decrease.
What contraindications for hemangioma should the patient be aware of?
The list of contraindications for spinal hemangioma includes:
- visiting saunas, solariums, prolonged exposure to the sun and other thermal effects;
- massage the affected area (provokes increased blood flow);
- manual therapy;
- physiotherapy;
- prolonged standing or sitting (more than 4 hours).
It is recommended to limit the intake of vitamins and immunostimulants, because such drugs can provoke the growth of tumors.
Is spinal hemangioma dangerous?
Hemangioma is dangerous if its course is uncontrolled. It can cause neurological disorders leading to a decrease in quality of life. There is a small chance of cells degenerating into cancer. The patient's condition must be monitored at all stages of treatment.
Where to go for diagnosis and treatment in Moscow?
If you suspect the development of a vertebral hemangioma in Moscow, you can contact JSC “Medicine” (clinic of Academician Roitberg), which has a convenient location in the Central Administrative District (Mayakovskaya metro station). Experienced staff will provide an individual approach, conduct an examination using high-quality equipment, differentiate the diagnosis and determine the best treatment regimen.
Dangerous dimensions
There are critical tumor sizes at which the risk of the above complications significantly increases. But a single, abstract size is not enough. Therefore, if you or your loved ones have a hemangioma measuring 1 cm, then this is not enough to determine the prognosis. If a large, massive man has this hemangioma in the fourth or fifth lumbar vertebra, then there is nothing to worry about. And if a young girl has a tumor of the same size in the third cervical vertebra, then this is extremely dangerous, and in this case it is necessary to be treated without waiting for complications.
Large hemangioma with compression of the spinal canal.
The situation is aggravated by the fact that with a hypothetical fracture of the 4th lumbar vertebra, no spinal cord at this level no longer exists, and, in extreme cases, cauda equina syndrome is possible, with the development of shooting pains in the legs, numbness of the perineum, the development of erectile dysfunction, and urinary disorders. In the case of a fracture of the third cervical vertebra, and progressive myelopathy or spinal cord injury, we are talking about quadriplegia, that is, complete paralysis of the arms and legs, severe disability and the same urination disorders. This is what “1 cm” means for prognosis without an exact indication of the level of hemangioma.
The danger of hemangioma also increases in proportion to its growth rate. Therefore, if a tumor of non-critical size is detected, only one thing is required: a re-examination after a year, if there are no complaints, then after another year, then, possibly after 3 years, then after 5 years. And if the tumor is truly stable, then there is no need to worry.
Another important criterion for danger is the location in the vertebral body. If the hemangioma is small, and it is located approximately in the center, and is surrounded on all sides by undestroyed bone beams that make up a single mass, then there is a high chance that the vertebra will remain strong for a long time, even if it grows evenly outward. But if the hemangioma is located close to the vertebral border, if only a thin bone edge separates it from the external space, then the risk of a compression fracture is much higher.
Cervical hemangioma with compression of the spinal canal
Finally, you should always keep in mind the condition of the bone tissue. If we are talking about a vertebral hemangioma in a young man, then there is no need to worry about bone density. But if a hemangioma is found in an elderly woman after menopause, then she will already have a high risk of osteoporosis, but in any case, the fragility of her spongy bone will be much higher. Therefore, even a small hemangioma in a patient with a high risk of osteoporosis will be more prognostically dangerous than a slightly larger tumor in a healthy person.
It follows from this that the main factor that frightens patients (namely, the size of the hemangioma taken by itself) does not play a decisive role in determining the degree of risk. But if you still focus on this indicator, then if the tumor begins to occupy a volume equal to 55-60% of the vertebral body, and at the same time there is a tendency for it to grow, then it is necessary to think about surgical treatment.
The doctor must explain to the patient that the slow growth of a hemangioma does not mean malignant growth, and even more so, has nothing to do with metastasis. If this is not done, the patient can be frightened and depressed, and, as is known, chronic depression and anxiety are one of the risk factors for chronic back pain. A hemangioma hidden inside a vertebra never hurts until bone destruction occurs. But if the patient is under stress, he may constantly complain of false back pain, which will significantly worsen the quality of life.
Pathogenetic features
As a rule, hemangioma forms in the vertebral body. However, there is also a small percentage of cases where the tumor appeared in other parts of the spine, in particular:
- in the posterior elements of the spinal column;
- in the paravertebral line;
- in the epidural space.
A study of the structure of such a tumor showed that inside it consists of two elements:
- soft tissue;
- bone
The structure of the vertebra itself in this case has the appearance of a honeycomb and consists of large and small cells.
Clinical symptoms
Vertebral hemangiomas have exactly the same clinical picture as Schmorl’s hernias, or rather, none at all. Although they have much in common: they destroy the bone tissue of the vertebrae, both of these formations are prone to enlargement, but still, both of these processes are completely asymptomatic. Even if we take the most delicate, cervical spine, the hemangioma still does not show any signs until one of the above-mentioned complications occurs.
And only in the rarest cases, when the tumor has reached a significant size, can a so-called vertebral collapse occur, in which a compression fracture actually occurs, but no separate fragments are formed, the parallelism of the overlying and underlying intervertebral disc is maintained, and the fracture itself is an impacted along the entire perimeter of the vertebral body. In other words, the vertebra seems to settle, its height decreases. In this case, naturally, there is a disruption of the natural course of the nerve roots in the corresponding foramina, and acute radicular symptoms appear.
Spinal hemangioma: symptoms
The size of the hemangioma, as a rule, does not exceed 1 cm, and in this case the symptomatology consists of aching pain in the back, but in some cases it may be absent altogether.
Spinal hemangioma, whose dimensions exceed those indicated, behaves somewhat differently. In this case, the pain will be more obvious and often recurring. The result of the growth of hemangioma can be subsidence of the spine, which entails disruption of normal intestinal function and numbness of the limbs.
Despite the benign nature of spinal hemangioma, the disease can trigger the thinning of bone tissue, which often causes a spinal fracture due to excessive physical exertion or injury.
About radicular symptoms
In this case, we are talking about the appearance of sharp, shooting pains, reminiscent of an electric shock. They are provoked by any movement, shaking of the spine, that is, coughing, laughing, sneezing, straining in the toilet. This pain occurs when older people experience a shooting pain in the lower back, or lumbago.
With the long-term existence of radicular symptoms, a secondary, myofascial-tonic syndrome occurs. The deep-lying back muscles near the affected vertebra react to the surrounding inflammation, to the impacted fracture, with constant, chronic spasm. As a result of spasm, the muscle is deprived of the ability to promptly remove lactic acid, that is, waste products. She is deprived of nutrition from the arterial capillaries, which are also spasmed. This situation forms a vicious circle, and it can be broken either by eliminating the defective vertebra, or, if it is impossible for some reason to carry out restorative surgery, by prescribing central muscle relaxants and wearing a corset with limited mobility in the back, but this is not the best way out. provisions.
How often does radicular pain occur with hemangiomas? Very rarely, out of all diagnosed vertebral hemangiomas in all parts, disc collapse with the development of radicular symptoms occurs in 0.1% of cases. Therefore, the main “suppliers” of radicular symptoms can be considered protrusions and herniations of intervertebral discs.
Preventive measures
Having learned what spinal hemangioma is, you can now prevent the development of complications. Preventive measures will prevent the disease from starting and not worsening the condition. It is necessary to see a doctor annually and monitor tumor growth. Benign neoplasms react very poorly to sunlight. With this disease, it is recommended to avoid solariums, long stays on the beach, avoid engaging in traumatic sports, and stop using immunostimulants.
Diagnostics
Computer and magnetic resonance imaging reign supreme in the diagnosis of hemangiomas. Even the term “diagnosis of vertebral hemangiomas” is absurd, since they do not hurt and do not manifest themselves in any way, and therefore there is no point in looking for them. This can only be done during a scientific study on the incidence of vascular tumors of the vertebrae.
Therefore, almost 100% of the detection of all hemangiomas are accidental findings. They begin to be monitored, and with a reasonable approach, seeing a growing vascular tumor, when it reaches a certain size, and taking into account the risk factors and dangers outlined above, radical treatment is carried out, which makes the patient forget about the hemangioma. In some cases, hemangioma is initially suspected during an X-ray examination of the spine, but to accurately confirm the diagnosis, the patient is still sent for a tomography. There are no other diagnostic methods, just as there are no laboratory tests for hemangioma.
Causes and risk factors
Hemangiomas occur in adult men and women with equal frequency. They can be congenital or caused by a hereditary factor, or they can arise during life under the influence of unfavorable conditions:
- spinal injuries;
- intense loads;
- mutagenic factors (radiation);
- carcinogenic substances in household chemicals and food.
In newborns, the risk of hemangioma increases in the following cases:
- if the pregnant woman was forced to take certain medications that affect the formation of the embryo;
- the child suffered an intrauterine viral infection;
- The pregnant woman experienced an exacerbation of endocrine diseases;
- pregnancy took place in an environment unfavorable from an environmental point of view;
- the pregnancy was multiple, premature, accompanied by preeclampsia or placental pathology;
- mother of a child over 35 years of age.
Hereditary hemangioma can appear in a baby from birth in any part of the spine or other organs
Treatment of patients with vertebral hemangioma
Since both stable and growing hemangioma are reliably hidden, as if inside a shell, inside a vertebra, then absolutely all conservative methods are completely ineffective, meaningless, and if they are offered to you, then this is nothing more than fraud.
Fraud includes attempts to “cure” hemangioma in such patients with the help of massage, acupuncture, osteopathy sessions, manual therapy, leeching, cauterization with wormwood cigars, electrical stimulation, electrophoresis sessions, and other techniques so beloved by our people. After the money is spent, the patient undergoes a second MRI. Hemangioma has not gone away! He comes to the doctor in anger, and the doctor with a charming smile informs the patient that “... you had a growing hemangioma, and we finally, using unique techniques, stopped its growth and achieved stabilization. Now you are in no danger, and you can forget about the operation”..... Comments, as they say, are unnecessary.
We must remember that a formation that is hidden inside a vertebra can neither be eliminated nor stop its growth without getting inside the vertebra itself. Fortunately, hemangioma can be treated with a simple, painless, and minimally invasive surgical method, without any incisions.
Percutaneous puncture vertebroplasty
Puncture vertebroplasty is a modern and very convenient method of removal. The goal is to eliminate the cavity inside the vertebra, filling it with special cement, which, when slightly heated, expands, completely destroys the tangle of blood vessels, and completely fills the entire space inside the vertebra.
Schematic representation of the procedure.
You don't need to make any cuts for this. It is enough to accurately determine the projection of the desired vertebra on the skin. Under X-ray control, to avoid mistakes, a needle is inserted into the vertebra under local anesthesia. After the needle falls into the internal cavity filled with a vascular tumor, a special biopolymer is fed inside, which is heated to a relatively high temperature, about 60 C°. This temperature is quite enough to completely destroy tumor cells, and the ability of the polymer to slightly expand during hardening makes it possible to guarantee that all voids are filled. Thus, the vertebra again becomes a single monolith.
In this case, a cementing substance consisting of:
- cement itself;
- radiopaque material (so that you can see the filling process directly under X-ray control “in real time”);
- antibacterial additive is approximately similar in density and mechanical characteristics to bone tissue, so that the vertebra continues to perform its function as before.
Cement.
Roughly speaking, this surgical intervention resembles filling a diseased tooth. No cuts, no blood, no long hospital stay. The next day, the patient can leave the hospital on his own, and local anesthesia allows percutaneous puncture vertebroplasty to be performed in patients with concomitant pathologies, including the elderly.
Contraindications for surgery
Taking advantage of the illiteracy of the population, many private clinics warm their hands well by doing the opposite - imposing unjustified surgical treatment. So, if they found a vertebral hemangioma on an MRI in a gullible, suggestible person, then they can make good money on this. Arguments such as “potential danger”, “risk of rapid, uncontrolled growth”, and “vertebral fracture in just a few weeks, or, in extreme cases, months” are used. Usually, urgent vertebroplasty is suggested, and the conversation ends with the words: “you are very lucky that you came to us, and we did the MRI on time.” Particularly arrogant “specialists” may even hint at the possibility of malignancy and “turning into cancer.” As we remember, this is impossible: hemangiomas of any location do not turn into “cancer”.
This is a very winning situation. Vertebroplasty is an operation with minimal risk for the patient, quite simple, but it can cost quite a lot of money. So, for the injection of bone cement into one vertebra you can easily charge 20 thousand rubles, and even more. Patients should know that this is not necessary at all, and they should not follow the lead of such doctors.
The contraindication to this small surgical intervention will be precisely the small size of the hemangioma and its stability. Therefore, if you are assured of the need for urgent vertebroplasty, then in any case, it is necessary to do a repeat tomography at least 6 months after the discovery of the tumor to make sure that the tumor is really growing and the potential danger.
Treatment
Treatment options range from observation with MRI to surgical resection. The choice of treatment method depends on the severity of symptoms and neurological symptoms.
Once a hemangioma is discovered, these patients should undergo regular evaluation to evaluate for the presence of compression fractures, neurological dysfunction, or extension into soft tissue. If pain and other symptoms occur due to hemorrhage or another cause, treatment will depend on the extent of the bleeding and the severity of neurological symptoms. The size and location of the hemangioma will also determine the treatment method.
Embolization is one of the most accessible treatment methods. In this procedure, a tiny catheter is inserted into the cavity of the hemangioma and a special foaming solution, such as polyvinyl alcohol, is poured. This material enters the bleeding area and the bleeding stops due to the formation of an embolus.
The most common treatment for hemangiomas is radiation therapy, which uses powerful X-rays to destroy tumor cells. Studies have shown that high doses of radiation therapy can not only stop tumor growth, but also significantly reduce pain. When compression of the spinal cord is accompanied by pain and impaired motor functions, surgical removal of the hemangioma may be required. In cases where partial tumor removal is performed, radiation therapy is necessary as an additional treatment. Surgical treatment is also more often used in children due to the harmful effects of radioactive radiation on the growing body. The presence of pain in the spine with hemangioma and neurological symptoms are signs that treatment is necessary. If symptoms increase quickly, then surgical treatment is recommended. However, if symptoms develop slowly, radiation therapy or embolization are considered better options.
Early diagnosis and treatment of symptomatic spinal hemangiomas is essential to prevent persistent and irreversible neurological deficits. Various treatment options, such as surgical decompression, endovascular embolization, radiation therapy and administration of pure alcohol or methyl methacrylate, or any combination of these methods, must be tailored to the individual patient. Supervised transpedicular percutaneous injection of pure alcohol for the treatment of symptomatic spinal hemangiomas is a new, simple, safe and effective method for rapidly reducing compression and devascularizing the hemangiomas. Further monitoring of the patient is necessary to assess the effectiveness of the procedure and detect possible complications or relapses.
A little history
It must be said that vertebroplasty is an extremely successful and beautiful way to eliminate a tumor and create a single bone block. Previously, before the introduction of this technique, sclerotherapy was used. In this case, a sclerosing substance, such as ethyl alcohol, was injected into the hemangioma. But the cavity remained: although the hemangioma itself died, the alcohol reduced the strength of the bone tissue, and as a result, a pathological fracture quite often occurred. In some cases, the tumor did not die completely, and a relapse occurred.
In addition to sclerotherapy, tumor embolization was also used, that is, an attempt to eliminate blood flow through the vessels. It was technically more difficult, and the matter could not be done with just a puncture. It required the skill of a vascular surgeon, which is not at all needed in modern vertebroplasty. But since the tumor itself remained, the death of the embolized vessels did not play a big role. The vessels actually died, but new vascular bundles were constantly being formed, because the pressure in the arterial section was maintained.
Etiology of the disease
To date, the etiology of the development of spinal hemangioma has not been fully studied. Previously, opinions regarding the origin of this type of tumor were divided into two points of view:
- the appearance of a tumor is the result of vasodilation;
- hemangioma is a true neoplasm.
In the 21st century, many research scientists believe that hemangioma is a benign tumor that appears as a consequence of genetic predisposition. This opinion is based on the fact that most of these formations develop at the site of embryonic clefts.
Forecast
As you may have guessed, in the vast majority of cases, a stable, small hemangioma does not affect either the quality of life or its duration. Before the widespread use of tomography, tens and even hundreds of generations lived perfectly well with hemangiomas, with calcification of the pineal gland in the brain, and with other random findings that nowadays cause stress and panic. It is not always necessary to take any emergency measures when you discover unfamiliar formations in your body.
Perhaps, if a “silent” vertebral hemangioma is detected, we can only advise you to keep your weight close to ideal, avoid heavy lifting, weightlifting, and contact, hard types of martial arts. Women can be advised to regularly perform densitometry after menopause, since in the presence of osteoporosis, a pathological fracture can occur long before the hemangioma reaches the theoretical strength limit in the region of 50-60% of the vertebral volume.
And if a compression fracture already occurs, then you will have to undergo extensive surgery. Yes, some vertebral compression fractures do not require surgical treatment; they heal on their own. But keep in mind that in this case there will be a vascular tumor between the bone fragments, and the hemangioma will be a factor of “non-union”, it will create tissue interposition between the fragments, and, lying freely, no longer covered by the vertebra, will create an additional risk of bleeding.
Therefore, the basis of the correct approach to the treatment of hemangiomas will be dynamic observation, taking into account additional risk factors.
Symptoms
Spinal hemangioma does not manifest itself in any way until the integrity of the vertebral body is compromised and the above-described disorders occur. Only in very rare cases is radicular syndrome observed, i.e., pinching of the nerves passing through the affected vertebra and the occurrence of:
- sharp, shooting pains along its course, caused by various movements, coughing, laughter;
- sensations of numbness, crawling;
- limited movement.
If the hemangioma is located in the cervical vertebra, cerebral circulation may be impaired, which will lead to headaches, dizziness, hearing, vision and sleep disturbances. When it is localized in the thoracic vertebra, disturbances in the functioning of the pelvic organs, heart, and digestive organs may be observed, and when a tumor forms in the lumbar vertebrae, there are frequent cases of pain radiating from the lower back to the groin and hips.
This is only possible when the hemangioma reaches a large size and leads to a compression fracture of the spine without the formation of individual bone fragments, which occurs only in 0.1% of patients with vertebral hemangioma. In such situations, the vertebra seems to be evenly flattened. As a result of a decrease in its height, the size of the natural openings through which the nerves pass also decreases, which leads to their compression and the development of radicular syndrome.
In the vast majority of cases, radicular syndrome occurs due to intervertebral hernia.
The patient must clearly understand that hemangioma, although it is a tumor, has nothing to do with oncology and is not capable of degenerating into a malignant neoplasm and giving metastases. This is very important to reduce stress levels and avoid the development of anxiety, since negative experiences weaken the body and false back pain may occur, which significantly reduces the quality of life.