Extensive myocardial infarction: causes, symptoms, diagnosis and treatment


Myocardial infarction: symptoms, signs of the need for first aid

Myocardial infarction in medicine is defined as the development of necrotic changes in the heart.
This is one of the most acute clinical forms of IHD (coronary heart disease). The disorder occurs due to acute insufficiency of blood flow due to a failure in the supply of oxygen to the heart muscle. A heart attack may be indicated by sudden sweating, nausea, pain in the sternum, forearm and other parts of the body. Heart attacks in men occur 5 times more often than in women, which is especially noticeable in young and middle-aged people.
Heart attacks in women develop on average 10-12 years later than in men. Among the reasons is the later development of atherosclerotic changes, which is facilitated by less widespread bad habits and the protective effect of estrogens in women.

Types of pathological process

Classification is carried out on several grounds.

Based on the form of functional impairment:

  • Circular. It is one of the heaviest types. Several branches of the coronary circulation are blocked (there are two arteries in total, each branching along the path into the tissue).

Generalized malnutrition leads to the impossibility of adequate trophism. Mortality is about 80%; with timely assistance and transportation to a hospital within the first hour, the chances increase slightly.

Partial work of the affected area may remain; necrosis is not always complete.

  • Transmural form. The exact amount of tissue involved is not known. But total necrosis of the area is observed, it is excluded from functional activity. Even with proper treatment and survival, severe heart failure develops for this reason.
  • Actually large-focal MI. When a group of areas is involved in the pathological process. They are usually located asymmetrically.

Depending on the location, we can talk about an infarction of the anterior or posterior wall of the heart. The first option is less noticeable from a clinical point of view; false symptoms or the absence of a clear picture are possible.

Classification is carried out according to the prevailing symptom complex, the involvement of third-party organs and tissues:

  • Cerebrovascular form. It can proceed in parallel with the classical one. The trophism of nerve clusters and cerebral structures is disrupted. The likely consequence is a stroke.
  • Arrhythmic type. The main manifestation is a violation of heart rate. Tachycardia or a decrease in heart rate occurs in parallel with a change in the intervals between beats. The process is represented by extrasystole, fibrillation.
  • Abdominal form. The clinical picture of an acute abdomen is typical. Nausea, vomiting, and unbearable pain in the abdominal cavity occur. Such patients are falsely mistaken for gastroenterological patients and sent to the appropriate department. Precious time is wasted and chances of survival are diminished.
  • Asthmatic appearance. Shortness of breath, impaired consciousness, asphyxia and other “delights” are included.

All four are called atypical, and together they account for barely more than 10% of clinical situations worldwide.

Causes of myocardial infarction

Myocardial infarction develops for various reasons, some of which are contributed by the person himself, others by his environment. Let us highlight 3 main groups of provoking factors:

  1. Factors that directly depend on the person - eating large amounts of fatty foods, smoking, excessive alcohol consumption.
  2. Factors that indirectly depend on a person are obesity, menopause and postmenopause.
  3. Factors that do not depend on a person - old age, genetic predisposition.

Myocardial infarction develops with atherosclerosis and inflammation in the walls of the arteries resulting from trauma, radiation exposure, vascular embolism, congenital anomalies and disruptions of the hematopoietic apparatus.

Heart attack: symptoms and first signs

  • Patients do not always associate symptoms of a heart attack with the manifestation of this pathology. The patient’s feelings depend on what period of its development the disease is at. Common signs of a heart attack:
  • severe dizziness, feeling of lack of air, shortness of breath;
  • feeling of chronic fatigue, cold sweat on the body;
  • uneven heartbeat, severe arrhythmia;
  • pain impulses in the arms, forearms, shoulders, side, sternum;
  • nausea, unpleasant heaviness in the stomach, loss of consciousness.

The first signs of a heart attack are not always obvious, but they attract attention. There are several periods of development of pathology:

  • Pre-infarction stage - the first signs here are increased fatigue, weakness, fatigue, a feeling of squeezing and rapid heartbeat. There is no significant pain yet. In a patient with myocardial infarction, the lips and nail plates turn blue, the pulse becomes erratic and uneven. At this time, the severity of the disease increases, the duration of the period ranges from a couple of hours to a month.
  • The most acute stage of heart attacks is pain. The patient begins to feel as if his chest is being squeezed in a vice. Behind the sternum there is a burning sensation, fiery heat, pulsating pain. With the development of an extensive heart attack, the pain is severe and prolonged. Strong and abrupt impulses are observed in young patients. Muffled pain, indicating myocardial infarction, is more often observed in patients with diabetes mellitus. The duration of the period is from half an hour to 2-4 hours. Complications that pose a direct threat to life are possible.
  • Acute stage of a heart attack - among the first symptoms, the final formation of a focus of dead tissue and the occurrence of life-threatening conditions are noted. The duration of the period is 2-14 days.
  • Subacute period - dead areas are replaced by connective tissue. The duration of the stage is 6-8 weeks.
  • The post-infarction period lasts from two months to six months. During this time, the body adapts to new conditions.

If there are signs of a heart attack, you should not self-medicate; you should urgently consult a doctor, undergo an examination and get specialist recommendations.

Where is the pain hidden during myocardial infarction?

Pain during myocardial infarction is localized in the chest area, spreading mainly to the left side of the chest space or being fixed in the central zone. The patient’s appearance also attracts attention: the skin is pale, moist, blue discoloration is visible in the area of ​​the nasolabial triangle.

Myocardial infarction is often characterized by pain spreading to the left or right arm. Patients often talk about unpleasant sensations in their wrists, so similar to being put on squeezing handcuffs. The pain can go to the left shoulder blade and spread around the neck. The abundance of such places often complicates diagnosis, especially since pain symptoms are cyclical, increase and disappear in waves, and then everything repeats again.

Sometimes symptoms are observed for several days, and people do not rush to see a doctor because they are not aware of the development of signs of a dangerous disease. Another interesting symptom of a heart attack is known, when a person experiences hallucinations against the background of acute intense pain.

Atypical forms of the disease attract attention when the symptoms and first signs of a heart attack are manifested not by pain, but by shortness of breath, a feeling of lack of air and an irregular heartbeat. Acute infarction develops when a focus of necrotic tissue is finally formed. At this time, the pain disappears, the pressure drops, and the pulse quickens. The pain may persist if the affected area during a heart attack expands.

Risk group

Character traits inherent in women such as caring for the family, worries about the fate of children, dedication and self-sacrifice contribute to their being at risk. Such women practically forget about themselves, do not care about their own health, ignore or simply forget about visiting a doctor for preventive purposes. Without paying due attention to the warning signs of the disease, they may end up in a situation where irreversible processes occur.

Women who live a lifestyle that is far from healthy are also at risk of having a heart attack. Those who engage in heavy (harmful) physical labor or suffer from chronic diseases are also not insured.

It is very important for women over 50 to see a cardiologist regularly.

Statistics show that the rate of cardiovascular disease is so high that women aged 30 or 40 may also be at risk. Therefore, preventive methods should be applied starting at an earlier age.

Scheme of development of myocardial infarction

The atherosclerotic plaque loses its integrity and undergoes rupture. Its surface is corroded by erosion, which provokes inflammation. Plaque rupture is possible under the following circumstances: increased blood pressure, serious and exhausting physical activity, smoking, etc.

A blood clot forms that blocks the lumen of the coronary artery (thrombosis). The blockage occurs due to the clumping of platelets. A thrombus forms inside the plaque when its membrane ruptures, and only then comes out, closing the lumen of the coronary artery. If the blockage is sudden, a through myocardial infarction develops with necrotization of the entire thickness of the heart muscle. This is one of the most severe forms of the disease due to the high risk of death.

The coronary artery narrows sharply. With spontaneous or drug-induced dissolution of a blood clot and incomplete blockage of the artery, non-through infarctions are formed.

Diagnosis and treatment for heart attack

An experienced doctor makes an accurate diagnosis at the first signs of illness. To help him - characteristic symptoms, a detailed clinical picture of a heart attack, electrocardiography indicators and identification of blood biomarkers indicating necrotic changes in the heart area. The first examinations upon treatment include a general blood test, biochemistry, echocardiography, and emergency selective coronary angiography.

Cardiologists deal with heart attacks; treatment depends on the severity of the pathology and how severe the symptoms are. The first signs of a heart attack in a woman or man indicate the need for urgent medical attention. The first and main tasks of doctors are to stop the development of necrosis of cardiac tissue, eliminate pain and associated complications.

In therapy, priority is given to the administration of painkillers, thrombolytic therapy, antiplatelet agents, and intravenous anticoagulants. In case of heart attacks, surgery of the heart muscle is possible - stenting and coronary artery bypass grafting.

What if the changes are no longer fresh?

If a microinfarction in the scar stage is detected on the ECG, the patient needs to deal with the prevention of more widespread changes in the myocardium.

Regular activities and nutrition do not differ from the general requirements. They should be followed throughout your life.

Diseases that contribute to myocardial ischemia are treated with specific drugs: antihypertensive drugs - hypertension, hypoglycemic drugs - diabetes.

A previous microinfarction indicates poor coronary circulation and developed atherosclerosis. Monitoring the level of lipoproteins in the blood and coagulation is necessary.

The doctor usually prescribes a course of statins if it is impossible to manage with a diet.


To reduce thrombosis, drugs based on acetylsalicylic acid (Cardiomagnyl, Thrombo Ass) are indicated.

According to indications for microinfarction, coronary lytics and β-blockers are prescribed. These drugs allow you to preserve and develop the remaining heart muscle tissue.

Prognosis after heart attacks

In case of heart attacks, you should be observed by a specialized specialist. After an illness, the situation may be complicated by cardiac arrhythmias, acute heart failure, cardiogenic shock, pericarditis, mental disorders and other pathologies. A professional doctor will help reduce the risks of exacerbations after myocardial infarction.

Our clinic provides services to patients with all types of cardiac pathologies, including those who have suffered a cerebral infarction (ischemic stroke). It is these complications of brain damage that are considered one of the main causes of increased mortality throughout the world. Despite this, our doctors do everything possible to maintain and improve the quality of life of their patients.

What diagnostic methods can be used to make a correct diagnosis?

The main method for diagnosing microinfarction is electrocardiography (ECG). Changes are characterized by the presence of:

  • coronary negative T wave;
  • downward shifted ST interval;
  • absence of disturbances of the ventricular QRS complex.

It is possible to establish the localization of the focus of necrosis by the ratio of changes in standard and chest leads, the depth of the lesion (usually subendocardial location). Transmural necrosis is not possible for small lesions.

When scars are identified after a microinfarction, bundle branch blocks and signs of metabolic disorders are detected.

Laboratory indicators are less typical and therefore are not very informative in diagnosis:

  • moderate leukocytosis is found in half of the patients;
  • acceleration of ESR up to 15-40 mm/hour;
  • a slight increase in fibrinogen concentration;
  • enzymes indicating myocardial necrosis may be normal.
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