Kudesan is a complex antioxidant in the treatment of cardiovascular diseases

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Kudesan q10 tablets with potassium and magnesium 40 pcs. Vneshtorg pharma

pharmachologic effect

Cardiotonic drug of non-glycoside structure.

Composition and release form Kudesan q10 tablets with potassium and magnesium 40 pcs. Vneshtorg pharma

1 ml of drops contains ubidecarenone 30 mg, as well as additional substances: ascorbyl palmitate, tocopherol acetate, citric acid, cremophor, sodium benzoate, water.

The children's drug in 1 tablet contains 7.5 mg of ubidecarenone. As additional substances: dextrose monohydrate, silicon dioxide, povidone, magnesium stearate, talc, creamy flavor.

Tablets for adults Kudesan Forte consist of 30 mg of ubiquinone and 4.5 mg of tocopherol acetate. Additional substances: colidon, aerosil, calcium stearate, primelose, microcrystalline cellulose.

Kudesan Forte in the form of a 1 ml solution contains 60 mg of coenzyme Q10 and 6.8 mg of tocopherol.

Kudesan with magnesium and potassium in 1 tablet includes: 7.5 mg of ubiquinone, potassium - 97 mg (in the form of potassium aspartate 450 mg), magnesium - 16 mg (in the form of magnesium aspartate 250 mg).

Kudesan Forte per 1 ml contains twice as much ubidecarenone and additionally contains tocopherol acetate.

Kudesan and Kudesan Forte drops for oral administration in 20 ml bottles.

Chewable tablets for children in contour packages of 30 pcs.

Kudesan Forte tablets, 20 pcs. packaged.

Kudesan with magnesium and potassium 40 pcs. packaged.

Characteristic

Coenzyme Q10, potassium and magnesium are required by the heart to function.

The main function of the heart is to ensure the movement of blood in the body through constant contractions. They, in turn, occur due to physical processes and biochemical reactions continuously occurring in the heart, which require significant energy expenditure.

Potassium and magnesium are essential participants, and the energy supply to the heart depends on coenzyme Q10.

With various diseases, emotional stress, intense physical work, as well as with the development of a number of age-related diseases, the load on the heart increases. Therefore, it requires more energy and nutrients.

“Cardio Potassium and Magnesium tablets” of the “Kudesan” trademark supplies the heart with the substances necessary for its full functioning throughout life.

Directions for use and doses

Adults: 2 tablets 2 times a day with meals.

Duration of treatment: 1 month.

Pharmacodynamics

Ubidecarenone (coenzyme Q10, ubiquinone) is a natural substance that is a vitamin-like coenzyme. Ubidecarenone is an endogenous substrate that takes part in the transfer of electrons in the transport chain of redox processes, in the process of energy exchange, and in the reaction of oxidative phosphorylation in the respiratory chain of cell mitochondria. Participates in the processes of cellular respiration, increasing the synthesis of adenosine triphosphoric acid (ATP). Has a clinically significant antioxidant effect. Protects cell membrane lipids from peroxidation. Reduces the area of ​​myocardial damage under conditions of ischemia and reperfusion. Ubidecarenone prevents QT interval prolongation and improves exercise tolerance. Due to endogenous synthesis, 100% satisfaction of the body's need for coenzyme Q10 occurs only until the age of 20. Endogenous synthesis of coenzyme Q10 is reduced in various diseases in both adults and children, as well as in the elderly.

Indications for use Kudesan q10 tablets with potassium and magnesium 40 pcs. Vneshtorg pharma

The drug is used as part of complex treatment and for prevention.

In adults:

  • cardiomyopathy;
  • heart failure;
  • arrhythmias;
  • myocardial infarction during the recovery period;
  • cardiac ischemia;
  • arterial hypertension;
  • preparation for aorto-coronary bypass surgery and other surgical interventions on the heart.

Instructions for use of Kudesan for children determine the possibility of taking it for the following diseases:

  • heart disease (cardiomyopathy, heart failure, arrhythmias);
  • preparation for operations for congenital and acquired defects;
  • kidney diseases (metabolic nephropathy, chronic pyelonephritis);
  • diseases of the nervous system (vegetative-vascular dysfunction, hereditary neurodegenerative diseases, muscular dystrophies, congenital myopathies);
  • chronic gastroduodenitis;
  • recovery period after operations and serious illnesses;
  • asthenic syndrome.

In children and adults, the drug is used to increase adaptation to increased physical activity and to compensate for the lack of coenzyme Q10 in the body.

Contraindications

individual intolerance; children under 1 year old.

If you have low blood pressure, use it with caution.

Application of Kudesan q10 tablets with potassium and magnesium 40 pcs. Vneshtorg pharma during pregnancy and breastfeeding

The drug is not recommended for pregnant and lactating women due to the lack of sufficient experience in clinical use.

special instructions

Impact on the ability to drive vehicles and operate machinery

The effect of the drug "Kudesan® for children" on the ability to drive vehicles and operate machinery has not been studied.

Overdose

Cases of drug overdose have not been described.

Side effects Kudesan q10 tablets with potassium and magnesium 40 pcs. Vneshtorg pharma

Allergic reactions are possible. Very rare: nausea, diarrhea.

Drug interactions

The simultaneous use of lipid-lowering drugs (statins, fibrates), beta-blockers (atenolol, metoprolol, propranolol), tricyclic antidepressants can lead to a decrease in the concentration of ubidecarenone in the blood plasma. Ubidecarenone may reduce the effect of warfarin.

Ubidecarenone can potentiate the effect of nitrates and enhance the antihypertensive effect of diltiazem and metoprolol.

Kudesan forte solution 20ml (Rusfik)

There is such a form of the drug as Kudesan forte. It is available in the form of drops and tablets. According to the instructions, it can be used in adults and children over 14 years of age. The main difference is the increased content of coenzyme Q 10. Due to the higher concentration of the active substance, fewer drops are required per dose, which is much more profitable than using a 3% solution. The main active ingredient of Kudesan is coenzyme Q10, which is used in the prevention and composition of complex therapy: cardiovascular failure, atherosclerosis, coronary heart disease, arterial hypertension; chronic fatigue syndrome; The main active ingredients - coenzyme Q 10 and vitamin E - are necessary components for protecting cellular structures from adverse environmental influences. When used together, the effectiveness of these substances is highest. Functions of Q10 in the body If you have purchased a product containing Q10 for the first time, you will benefit from additional information about this substance. The scientific research that discovered the biological role of coenzyme Q10 was one of the largest achievements in the field of human biochemistry and was awarded the Nobel Prize. Due to its high efficiency, Q10 has become widely known, especially in cardiology. Coenzyme Q10 is a substance natural to the body. It is produced and present in all cells of the body. Causes and consequences of Q10 deficiency If the synthesis of Q10 in the body decreases, energy production and the preservation of cellular structures are disrupted. As a result, fatigue appears, activity decreases, heart function is disrupted, immunity weakens, etc. Q10 deficiency and a decrease in its synthesis can occur due to various diseases, medications, and heavy physical and mental stress. Its causes may be age-related disorders, metabolic failures, etc. You should also know that, starting from the age of 20, regardless of health and lifestyle, the synthesis of Q10 in the human body begins to decline. How to eliminate Q10 deficiency It is almost impossible to compensate for the Q10 deficiency by increasing its intake from food, because the Q10 content in most foods is low. So, in order to deliver the required amount of Q10 to the body per day, you need to eat at least 800 g of beef or 1 kg of peanuts. In order to eliminate Q10 deficiency and normalize its natural synthesis in the body, additional intake of Q10 is recommended. The natural origin and presence of Q10 in all cells determine the safety of its preparations. The possibility of overdoses, side effects and negative drug interactions is minimized. Efficiency of use The effectiveness of Q10 preparations depends on the form of release. Q10 is a fat-soluble substance (that is, it is absorbed only with fat). Most Q10-based drugs have to be taken with fatty foods, which is not very beneficial. Domestic specialists have developed and patented a technology that has made it possible to convert the poorly digestible fat-soluble substance Q10 into a water-soluble form that is optimal for absorption and easy to use. This technology is used in the production of Kudesan series drugs. Information for specialists Coenzyme Q10 is a vitamin-like compound present in all tissues of the human body. Most Q10 is found in the heart. The main function of Q10 is to couple oxidative phosphorylation reactions in the mitochondrial respiratory chain. Without Q10, insufficient ATP is produced. The second function of Q10 is to quench free radicals and restore the activity of other antioxidants. Q10 is synthesized endogenously, but from age 20, Q10 biosynthesis progressively decreases. In the myocardium, by the age of 50, Q10 deficiency reaches 40% and deepens with age. With a deficiency of Q10, negative changes occur in the cardiovascular system: myocardial contractility decreases, the risk of atherosclerosis, coronary heart disease, myocardial infarction, etc. increases. The effectiveness of Q10 in complex therapy and prevention of these diseases, as well as for slowing down processes associated with aging, has been established. . Coenzyme Q10 is recommended in complex therapy: with GM-CoA reductase inhibitors (statins) to level out side effects (such as myalgia, peripheral neuropathies); diseases caused by mitochondrial dysfunction (myopathies, asthenia); heart rhythm disturbances, vegetative dystonia, chronic gastroduodenitis, chronic pyelonephritis, nephropathy in pediatric practice. And also in case of malnutrition, growth retardation, during the period of convalescence after serious illnesses and surgical interventions. Coenzyme Q10 can be recommended for the prevention of chronic fatigue syndrome and asthenic syndrome. Water-soluble form of Q10 – ensures the most complete absorption. Prescribed doses of Q10: 30 to 150 mg/day. The recommended duration and frequency of use of Q10 is 2 months, 2 times a year.

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