How does validol affect blood pressure?

Validol is often prescribed as a combination therapy for the treatment of angina. It can be purchased in pharmacies in free form in the form of tablets, capsules and drops.

Validol under pressure is used in combination with other drugs. It has a calming effect and promotes the dilation of blood vessels, which reduces their load, normalizes blood flow and thereby reduces pressure.

Despite its effectiveness, in case of a severe crisis you can only count on a calming effect, because the indirect effect of the drug will not be able to adequately reduce blood pressure to the desired values ​​in a short time. People with hypotension are also advised to use the drug with caution.

What does Validol help with?

Many people know about the effect of the drug, but self-medication is not recommended. A doctor's consultation is required before use.

Most often, Validol is prescribed in the presence of the following conditions and diseases:

  • cardialgia;
  • angina pectoris;
  • disruption of the central nervous system;
  • states of hysteria;
  • headaches caused by the use of nitrates.

It is also effective against motion sickness. This condition is manifested by nausea and vomiting.

Drug and heart disease

Validol is often used for pathologies of the “main engine”; it helps eliminate pain in the heart and head. In the absence of contraindications, it is suitable for long-term use.

Basically, blood pressure increases with bradycardia, angina or pre-infarction, and with these pathologies the drug can harm the patient.

This is due to the fact that only the symptoms are alleviated and the person receives relief, but the contraction of the heart itself persists and soon leads to a heart attack or necrosis of cardiac tissue.

In this case, it is quite difficult for a doctor to make a diagnosis, since the picture of the pathology is blurred.

How to take Validol tablets

Before using the medicine, you should conduct a test that will help determine the body's reaction to the constituent substances. This will also allow you to determine how many tablets you can take per day without harm to the body.

The instructions indicate that the tablets should be placed under the tongue. They do not need to be swallowed or split, but kept until completely absorbed. The maximum dose is 10 tablets per day. The average duration of treatment is a week. If after taking it for 7-10 minutes no effect is achieved, then you should think about taking other medications.

When is it appointed?

Due to its sedative and hypotensive properties, the drug has a wide range of indications. It is prescribed for:

  • Mental overload, stress, neuroses.
  • Hysteria.
  • Pain in the area of ​​the heart, sternum. But only in case of pain, pressing discomfort, it is better to exclude Nitroglycerin.
  • Hypertension.
  • Seasickness.
  • Cardiopalmus.
  • Convulsions are provoked by cervical and thoracic osteochondrosis.

It does not accumulate in the body and has virtually no side effects.

How to use Validol drops

The medicine in the form of drops is used by placing it under the tongue. 5-6 drops per day are enough, which must be diluted in advance in a weak sugar solution. If necessary, the dosage can be increased only as directed by a specialist.

If the desired result is not achieved after taking it, the doctor may advise switching to an analogue or prescribing the additional use of other drugs.

The medicine in any form can be used with other drugs. Sometimes the parallel use of Validol and drugs with sedative effects can enhance the effect of the latter.

Validol

Validol

Registration number : LP-000612

Trade name : Validol

Group name : Levomenthol solution in menthyl isovalerate&

Dosage form: sublingual tablets.

Compound:

Active ingredient: levomenthol solution in menthyl isovalerate (validol) 0.06 g.

Excipients: sucrose (sugar) – 0.9216 g, calcium stearate monohydrate – 0.0098 g.

Description: flat-cylindrical tablets, beveled and scored, white with a yellowish tint with grayish inclusions, with a characteristic menthol odor

Pharmacotherapeutic group: coronary dilating agent of reflex action.

ATX code : [C01EX]

Pharmacological properties

Pharmachologic effect. It has a sedative effect and has a moderate reflex vasodilator effect due to irritation of sensitive nerve endings. Stimulates the production and release of enkephalins, endorphins and a number of other peptides, histamine, kinins (due to irritation of mucosal receptors), which are actively involved in the regulation of vascular permeability and the formation of pain. When administered sublingually, the therapeutic effect occurs on average within 5 minutes, with up to 70% of the drug released within 3 minutes.

Pharmacokinetics. When administered sublingually, levomenthol is absorbed from the oral mucosa, metabolized in the liver and excreted by the kidneys in the form of glucuronides.

Indications for use

Functional cardialgia, hysteria, neuroses, headache while taking nitra-

Tov, motion sickness syndrome (nausea, vomiting due to sea and air sickness).

Contraindications

Hypersensitivity, sucrase/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption (since the drug contains sucrose).

Carefully

With diabetes mellitus (the drug contains sugar).

Use during pregnancy and breastfeeding

Prescription of the drug during pregnancy and breastfeeding is possible if the expected benefit to the mother outweighs the potential risk to the fetus and child.

Directions for use and doses

Validol is prescribed to adults, 1 tablet under the tongue until it is completely absorbed. Take 1 tablet 2-3 times a day. The frequency and duration of administration is determined depending on the effectiveness of treatment. If the therapeutic effect is absent or insufficiently expressed, another therapy must be prescribed within the next 5-10 minutes after administration.

Side effect

Nausea, lacrimation, dizziness.

Overdose

Symptoms: headache, nausea, agitation, cardiac dysfunction, sharp decrease in blood pressure, depression of the central nervous system.

Treatment: discontinue the drug. Symptomatic therapy.

Interaction with other drugs

When used together with drugs that depress the central nervous system, it enhances the effect of the latter.

The simultaneous use of Validol with nitrates reduces the headache that occurs when using them.

special instructions

Should be prescribed with caution to patients with diabetes mellitus (for medicines containing sugar).

When taking Validol, you must be careful when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Release form

Sublingual tablets 60 mg.

10 tablets in a blister pack made of polyvinyl chloride film and aluminum foil.

2 or 3 blister packs together with instructions for use are placed in a cardboard pack for consumer packaging.

It is allowed to place blister packs with an equal number of instructions for use in a cardboard box (multiple packaging).

Storage conditions:

In a dry place, protected from light, at a temperature not exceeding 25°C.

Best before date:

3 years. Do not use after the expiration date.

Units:

pack

Contraindications

Consultation with a specialist is necessary to ensure there are no contraindications. These include:

  • excessive sensitivity to the constituent elements;
  • tendency to develop allergies;
  • myocardial infarction;
  • arterial hypotension;
  • age up to 18 years.

People who suffer from diabetes should take it with caution. If it is not possible to refuse taking it, then you need to regularly monitor the patient’s condition and even with minor deterioration you should consult a doctor.

Effect on pressure

Taking Validol in combination with other substances during a hypertensive crisis relieves pain and spasms. When a patient suffers from osteochondrosis, the drug reduces discomfort in the neck and sternum.

The drug is also indispensable for heart diseases, when the slightest stress or physical activity overwhelms the patient, increases the pulse rate, increases blood pressure and causes pain in the sternum.

One tablet can normalize the condition until the ambulance arrives.

A person's blood pressure can be either low with hypotension or high with hypertension.

With a sharp increase in pressure, Validol relieves spasms and dilates blood vessels, which, in combination with other medications, reduces pain and normalizes blood flow. As a result, the pressure drops, but in case of a severe attack, such treatment will not save the patient.

The drug is often used for atherosclerosis, as it eliminates the narrowing of blood vessels, which prevents blood from entering the brain. But this does not affect the reason itself in the form of strong pressure in the Validol stream.

Side effects and symptoms of overdose

With long-term use, the following side effects may occur:


  • feelings of nausea;

  • tearfulness;
  • feelings of loss of orientation in space and dizziness;
  • low blood pressure (hypotension is transient);
  • drowsiness;
  • increased flatulence (discharge of intestinal gases);
  • allergic reactions (Quincke's edema, rash on the skin and mucous membranes, itching).

After stopping taking Validol, the symptoms quickly disappear on their own.

Symptoms of exceeding the dose of this medication are a clear manifestation of side effects in combination with nervous excitement, cardiac dysfunction, a drop in blood pressure and depression of the functions of the central nervous system.

In case of overdose and symptoms of poisoning occur, it is necessary to immediately discontinue the drug, organize gastric lavage and administer desensitizing agents.

Composition of validol

In order to understand how validol affects blood pressure, you need to get acquainted with its composition. Knowing how the drug works, namely whether it increases or decreases blood pressure, is important for all people whose blood pressure is not normal. Otherwise, you can simply harm your health.

The drug is available in tablets and drops. The components included in its composition do not cause harm to health. Among them:

  • Valerian. It contains organic acids: formic, acetic, malic, stearic, palmitic. It is a sedative, helps get rid of insomnia, and has a positive effect on the functioning of the heart.
  • Menthol. Present in validol in the form of a special solution in valerian ether. It has a sedative effect, relieves tension, anxiety, irritability, dilates coronary vessels, and acts as an antispasmodic.

Mechanism of action and composition of the drug

Validol refers to drugs that have a stimulating effect on peripheral nerve receptors located in the mucous membranes. In addition to the main component of the medicine, there are auxiliary ingredients.

SubstanceGroupMechanism of actionEffect
A solution of menthol in isovaleric acid menthyl esterDrugs with reflex actionIrritation of peripheral nerve endings (cold receptors) leads to the release of opioid proteins (endorphins, enkephalins, dynorphins), which reduce pain and affect vascular permeability. The cutaneous-visceral reflex is triggered: local vasoconstriction correlates with an improvement in the trophism of the internal organs (corresponding to the innervation of the segment). Local: irritant, anti-inflammatory. Remote (reflex): expansion of coronary vessels (antianginal), toning of vein walls, analgesic effect, mild hypnotic effect (due to depression of the central nervous system)
Calcium stearateBasic toolsStabilizer of a mixture of different components, ensures the plasticity and integrity of the final substance
SugarSweetenersImproves organoleptic (taste) qualities

The composition of Validol is based on menthol. The most significant effect is the ability, when irritating receptors in the oral mucosa, to trigger a reflex arc, which leads to dilation of the coronary vessels.

According to the instructions, this pharmacological agent is available without a prescription.

Does it make sense to use it at high blood pressure?

With high blood pressure, the blood vessels are narrowed, and validol acts as a vasodilator. In addition, it is a sedative, that is, it calms, as a result of which the heart rate normalizes, blood circulation improves, and pain disappears. Thus, we can conclude that the drug lowers blood pressure and its use for hypertension is quite justified. However, doctors note that validol cannot be considered a drug that lowers blood pressure. It can be prescribed as an additional agent in complex therapy.


Validol can be found in every family's medicine cabinet.

There is an opinion that if it lowers blood pressure, it is indirectly, and only in those cases when its jump is associated with:

  • with stress;
  • with increased nervousness;
  • with insomnia;
  • with overstrain and fatigue;
  • with excitement;
  • with emotional excitement.

If validol is able to eliminate all of the above factors as a sedative and vasodilator, it is quite possible that the pressure will indeed normalize as a result. And this will happen because the person will simply calm down. In case of arterial hypertension due to other causes, this drug is unlikely to help.

Doctors warn that it can be dangerous to use validol to lower blood pressure in the presence of heart disease (bradycardia, pre-infarction), as this can only worsen the condition. Not only will this drug not lower blood pressure or relieve pain, it can cause a heart attack. In case of illness, it is better to take heart medications prescribed by your doctor.

What is the real purpose of validol?

Its range of applications is quite wide. Indications include the following conditions:

  1. Angina pectoris. In the case of this disease, validol is prescribed as one of the drugs in complex therapy.
  2. As a mild sedative, it is indicated for various neuroses: neurasthenia, hysteria, obsessive states, and also helps to recover from stress and depression. As a rule, it is prescribed in combination with other drugs.


Validol is available in tablet form

Despite the fact that validol is considered harmless, it still has a number of contraindications that you need to remember when you have the product in your home medicine cabinet. It should be taken with great caution or avoided in the following cases:

  • for diabetes mellitus;
  • with individual intolerance to menthol and valerian.

With prolonged and uncontrolled use, side effects may occur: lacrimation, nausea, dizziness.

Low pressure application

In turn, those who suffer from hypotension may be interested in the question of whether validol increases or decreases blood pressure, and whether it can be taken by hypotensive patients as a sedative.

Doctors warn people suffering from low blood pressure that this drug may be dangerous for them. In this case, taking validol can lead to a drop in blood pressure, which may result in changes in the brain due to oxygen starvation. Therefore, hypotensive patients should consult a cardiologist for advice before taking validol. If your blood pressure is consistently low, it may be worth finding another drug with a similar effect.

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