Many people take Andipal tablets for blood pressure, not understanding how this effect is expressed, but appreciating its quick and mild hypotensive effect. The drug contains analgesic and antispasmodic components, due to which blood vessels and smooth muscles relax, and the hypotensive effect is secondary. However, doctors successfully use Andipal, prescribing it for the initial stages of hypertension and other concomitant diseases. How the product works, what its composition is, indications and methods of use will be discussed further.
Pharmacodynamics and pharmacokinetics
This is a combined drug that has a vasodilator, analgesic and analgesic effect. A good antispasmodic, which determines the use of Andipal for blood pressure.
Metamizole sodium, which is part of the composition, reduces body temperature and relieves pain. Once in the gastrointestinal tract, the substance is well and quickly absorbed and blocks the prostaglandin system of arachidonic acid, increasing the sensitivity threshold of pain centers in the hypothalamus .
Papaverine hydrochloride dilates blood vessels (reduces the level of calcium in cells) located on the periphery and significantly reduces the overall tone of the smooth muscles of the surface of internal organs.
Bendazole is an antispasmodic, dilates blood vessels, stimulates the spinal cord, and restores nerve endings in the periphery.
Phenobarbital exhibits its sedative properties and enhances the effects of other components of the drug.
Pharmadynamics and pharmacokinetics
Andipal begins to act 15 minutes after administration. This is due to the fact that the active components of the drug are quickly absorbed into the blood. The condition of a person with high blood pressure is normalized by improving cerebral circulation and stopping the release of adrenaline.
Analgin, entering the body, helps reduce the pain symptoms of migraines. The substance also reduces the severity of swelling in soft tissues, which provokes an increase in body temperature.
Papaverine eliminates spasms of smooth muscles in the digestive organs and in the walls of blood vessels. By dilating the arteries, blood flow improves.
Dibazol reduces heart rate and normalizes breathing. Phenobarbital in the drug has a sedative effect on the cells of the central nervous system.
Indications for use of Andipal. What does it help with?
Andipal tablets, what are they for?
- Indications for the use of the drug are migraines of various types.
- Pain associated with spasms of cerebral vessels in the head.
- The medicine helps against pain caused by spasms of smooth muscles or internal organs of the gastrointestinal tract.
- For mild forms of hypertension, it can be used as blood pressure pills.
What blood pressure should I take the medicine for? For primary or secondary hypertension, Andipal can be taken for high blood pressure.
Doctor's recommendations online
When taking Andipal for blood pressure, a rapid therapeutic effect is observed. Its effectiveness is evidenced by reviews from patients suffering from hypertension. Before using the product, you must ensure that there are no contraindications. If you take the medicine for hypotension or to relieve a hangover, you can get negative consequences in the form of nausea, weakness and an allergic reaction. The medication is suitable for one-time or short-term use. For course treatment, Andipal is taken only with the consent of the doctor, since it affects the composition of the blood and is addictive.
Contraindications
- Acute increased sensitivity to the constituent substances of the drug (especially pyrazolone).
- For glucose-6-phosphate dehydrogenase deficiency, various blood diseases, porphyria.
- Severe dysfunction of the kidneys and liver, tachyarrhythmia , angina pectoris, intestinal obstruction .
The use of the drug is contraindicated for children under 8 years of age during lactation.
Prevention of intracranial pressure in adults at home
Prevention of increased ICP is the prevention of various diseases affecting the cranial cavity.
This includes protection against infections that can affect the brain - vaccination against meningococcal and hemophilus influenzae infections, influenza vaccination. It is also necessary to treat various pathologies that can affect brain function. General recommendations are simple:
- follow a daily routine and lead the healthiest lifestyle possible;
- avoid head injuries;
- protect yourself from stress and nervous overload;
- Get enough sleep.
Side effects
According to the annotation: constipation , nausea , various allergic reactions ( conjunctivitis , urticaria, Quincke's edema ), nephritis , red urine , drowsiness , increased sweating .
With long-term use, agranulocytosis , leukopenia , and thrombocytopenia .
Before use, you should consult your doctor.
Instructions for use of Andipal (Method and dosage)
How to use the drug? Inside. Adults should take 1-2 tablets 2-3 times a day. The full course of treatment should take 7-10 days.
Before taking the medicine, consult your doctor. The course of treatment should be prescribed by a specialist, depending on the nature of the disease and its course. It is not recommended to take the drug for more than 10 days.
How to take if you have high blood pressure? Does Andipal increase or decrease blood pressure?
The drug has a hypotensive effect and is used for high blood pressure. Cannot be used for hypotension, this can lead to harmful changes in the brain.
Reviews
Irina, 34 years old: Andipal helps me with pressure surges - I take one tablet and after 15-20 minutes I feel much lighter. I don’t have chronic hypertension, so I don’t take pills in courses, but only during exacerbations. The doctor recommended that, in addition to medications, I also go on a diet (I’m overweight), I think this will help me quit taking pills completely.
Larisa, 42 years old: I take Andipal in courses because my blood pressure regularly fluctuates. I take 2 tablets a day for 5–7 days, then take a break for 3–4 weeks (as prescribed by the doctor). The product acts gently, reduces blood pressure quickly, I am satisfied with its effect. In addition, Andipal is sold in all pharmacies and is inexpensive.
Elena, 29 years old: I often had a headache, tinnitus, nausea appeared before vomiting. I went to the doctor, and it turned out that I had the initial stage of hypertension, although I had never had any problems with blood pressure before. I was prescribed a general massage, swimming, a salt-free diet and taking Andipal for high blood pressure. The drug is good, it eliminates headaches quickly, it even helps with abdominal pain, I will continue to take it on the doctor’s advice.
Interaction
The use of astringents, enveloping agents and activated carbon reduces absorption in the gastrointestinal tract.
When combined with other antispasmodics and sedatives, the hypotensive effect of the drug is enhanced. diabetes medications increases . Enhances the effect of glucocorticosteroids , Indomethacin and ethanol . Reduces the concentration of cyclosporine in the blood.
Inducers of microsomal liver enzymes ( barbiturate , phenylbutazone ), analeptics ( camphor , Cordiamin ), tonics ( Eleutherococcus , ginseng root) reduce the effectiveness of the drug.
Modern methods of treatment
In some cases, the patient does not require treatment; he is observed and treated for the underlying disease, which caused the increase in ICP.
If it is necessary to treat pathology, two approaches are used - conservative and surgical.
Conservative interventions are carried out for those patients whose ICP elevation is chronic and there is no significant deterioration of the condition over time. The basis of treatment is drugs that have a diuretic effect, which reduce the volume of fluid in the head. The specific medicine is determined by the level of pressure and the situation. In severe and acute processes, osmotic diuretics (mannitol) are used, in chronic cases - furosemide, hydrochlorothiazide, spironalactone. While taking them, you need to drink a potassium preparation - Asparkam, Potassium orotate, Panangin.
Surgical methods for treating increased ICP depend on the stage and severity of the disease. In acute situations, craniotomy is performed to reduce fluid pressure on the brain and drain excess fluid. Special shunts (tubes) are installed as planned, which drain fluid from the brain into the abdominal cavity.
special instructions
With long-term use of Andipal, the overall picture of peripheral blood should be monitored.
It is recommended to be careful and vigilant when working with mechanisms, due to the fact that the drug significantly affects the change in the reaction rate.
Does the medicine lower or increase blood pressure?
The medicine lowers blood pressure.
At what pressure should Andipal be taken?
With high blood pressure.
Andipal should be used as a medicine for blood pressure after consulting a doctor.
Symptoms of intracranial pressure in adults
In many cases, a slight increase in ICP may not manifest itself for a long time. If the pressure rises sharply or high enough, the following symptoms may occur:
- headache - it can be pressing or bursting, usually occurs in the morning, this pain has no clear localization, it can be felt in different parts of the skull;
- nausea and vomiting - they usually occur at the peak of the headache;
- drowsiness, malaise, general poor health;
- memory impairment (forgetfulness), attention disorders, problems with thinking;
- changes in the autonomic nervous system – surges in blood pressure, slow pulse, increased sweating;
- visual impairment up to complete blindness.
Symptoms may come on suddenly or develop gradually over weeks or months.
Analogues and substitutes
Level 4 ATC code matches:
Analdim
Reopirin
Tempalgin
Spazgan
Benalgin
Pentalgin ICN
Pentalgin N
Pentalgin
Analgin
Renalgan
Tetralgin
Spasmalin
Maxigan
Sedal-M
Piralgin
Baralgin M
Sedalgin Plus
Baralgetas
Revalgin
The drug has no analogues in terms of its main active ingredient.
Analogs for antispasmodic effect:
- Nomigren
- Papazol-UBF
- Papazole
- Urolesan
- No-Shpalgin
- Unispaz
- Teodibaverin
Safe interval
Compatibility between Andipal and alcohol is impossible. The patient must be sober. The drug can be taken no earlier than 12-15 hours after the person drank alcohol. This rule only applies if the dose of alcohol was insignificant.
You should be careful about your health. Taking medications is almost always incompatible with alcohol. And andipal is no exception. In order for the treatment to give positive results, you need to carefully read the instructions for the drug and strictly follow the doctor’s instructions.
Price for Andipal
Andipal tablets in Russia will cost about 40 rubles per pack of 20 pieces.
In Kyiv pharmacies the price of tablets will be about 20 UAH. for 10 pcs.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Andipal Avexima tablets 10 pcs. Avexima Siberia LLC
55 RUR order - Andipal avexima tab. n20 LLC Avexima Siberia
84 rub. order
- Andipal tablets 20 pcs. PharmstandardPharmstandard-Leksredstva OJSC
47 RUR order
- Andipal tablets 10 pcs. PharmstandardPharmstandard-Leksredstva OJSC
19 rub. order
- Andipal tablets 20pcs JSC "PFK Obnovlenye"
84 rub. order
Pharmacy Dialogue
- Andipal tablets No. 10Asfarma
67 RUR order
- Andipal (tab. No. 20)Updating PFC CJSC
90 rub. order
- Andipal (tab. No. 10) FS.-Leksredstva
15 rub. order
- Andipal (tab. No. 20) FS.-Leksredstva
37 RUR order
- Andipal Avexima tablets No. 20 Anzhero-Sudzhensky chemical-f.z.
83 RUR order
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Pharmacy24
- Andipal forte No. 100 tablets PAT Monfarm, Ukraine
154 UAH.order - Andipal V No. 10 tablets PAT Monpharm, Ukraine
16 UAH order
- Andipal forte No. 10 tablets PAT Monpharm, Ukraine
17 UAH order
- Andipal-V No. 100 tablets PAT Monpharm, Ukraine
152 UAH order
PaniPharmacy
- Andipal tablets Andipal B tablet. No. 10 Ukraine, Monfarm JSC
21 UAH order
- Andipal-Forte tablets Andipal-Forte tablets. No. 100 Ukraine, Monfarm JSC
171 UAH order
- Andipal tablets Andipal-B tablet. No. 100 Ukraine, Monfarm JSC
194 UAH order
- Andipal-Forte tablets Andipal-Forte tablets. No. 10 Ukraine, Monfarm JSC
22 UAH order
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Composition and release form
Andipal is available in the form of round tablets of white or yellowish color. There are distinctive marks on the surface of the tablets. At the pharmacy, the drug is sold in cardboard or paper packages containing 10 tablets of the drug.
1 pill contains the following active ingredients:
- analgin – 0.25g;
- dibazol – 0.02 g;
- papaverine – 0.02 g;
- Phenobarbital – 0.02 g.
Among the auxiliary components of the medication are:
- potato starch – 47.7 mg;
- talc – 9.25 mg;
- stearic acid – 2.9 mg.
